[PDF][PDF] Curcumin inhibits hepatic protein‐tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose‐fed rats

JM Li, YC Li, LD Kong, QH Hu - Hepatology, 2010 - Wiley Online Library
High consumption of dietary fructose is an important contributory factor in the development
of hepatic steatosis in insulin or leptin resistance. We investigated the effects of curcumin on …

Curcumin attenuates diet‐induced hepatic steatosis by activating AMP‐activated protein kinase

MY Um, KH Hwang, J Ahn, TY Ha - Basic & clinical …, 2013 - Wiley Online Library
Curcumin is a well‐known component of traditional turmeric (C urcuma longa), which has
been reported to prevent obesity and diabetes. However, the effect of curcumin on hepatic …

Curcumin inhibits lipolysis via suppression of ER stress in adipose tissue and prevents hepatic insulin resistance [S]

L Wang, B Zhang, F Huang, B Liu, Y Xie - Journal of lipid research, 2016 - ASBMB
Curcumin is natural polyphenol with beneficial effects on lipid and glucose metabolism and
this study aimed to investigate the effects of curcumin on lipolysis and hepatic insulin …

Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter‐4 and increasing glucokinase

Y Tang, A Chen - British journal of pharmacology, 2010 - Wiley Online Library
BACKGROUND AND PURPOSE Hyperleptinemia is commonly found in obese patients,
associated with non‐alcoholic steatohepatitis and hepatic fibrosis. Hepatic stellate cells …

[HTML][HTML] Curcumin analog CUR5–8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity

ES Lee, MH Kwon, HM Kim, HB Woo, CM Ahn… - Metabolism, 2020 - Elsevier
Objective Nonalcoholic fatty liver disease (NAFLD) occurs when excess fat storage in the
liver and it is strongly linked with metabolic syndrome including obesity, insulin resistance …

[HTML][HTML] Tetrahydrocurcumin ameliorates free fatty acid-induced hepatic steatosis and improves insulin resistance in HepG2 cells

JW Chen, ZL Kong, ML Tsai, CY Lo, CT Ho… - journal of food and drug …, 2018 - Elsevier
Elevated levels of free fatty acids (FFAs) in the liver, resulting from either increased lipolysis
or imbalanced FFAs flux, is a key pathogenic factor of hepatic steatosis. This study was …

Curcumin improves glycolipid metabolism through regulating peroxisome proliferator activated receptor γ signalling pathway in high-fat diet-induced obese mice and …

Y Pan, D Zhao, N Yu, T An, J Miao… - Royal Society …, 2017 - royalsocietypublishing.org
Curcumin is an active component derived from Curcuma longa L. which is a traditional
Chinese medicine that is widely used for treating metabolic diseases through regulating …

Dietary curcumin enhances insulin clearance in diet-induced obese mice via regulation of hepatic PI3K-AKT axis and IDE, and preservation of islet integrity

Y Kim, M Rouse, I González-Mariscal, JM Egan… - Nutrition & …, 2019 - Springer
Background Although type 2 diabetes mellitus (T2DM) is primarily characterized by
sustained high levels of circulating glucose, other factors, such as obesity, chronic …

Curcumin attenuates hepatic fibrosis and insulin resistance induced by bile duct ligation in rats

A Eshaghian, A Khodarahmi, F Safari… - British Journal of …, 2018 - cambridge.org
Recent studies have strongly indicated the hepatoprotective effect of curcumin; however, the
precise mechanisms are not well understood. This study aimed to determine the protective …

Curcumin inhibits hyperlipidemia and hepatic fat accumulation in high-fructose-fed male Wistar rats

N Maithilikarpagaselvi, MG Sridhar… - Pharmaceutical …, 2016 - Taylor & Francis
Context: Curcumin, an active principal of Curcuma longa Linn.(Zingiberaceae), has potent
antioxidant and anti-inflammatory properties. Objectives: This study investigated the effects …