The RNA-processing exosome contains ribonucleases that degrade aberrant RNAs in
archael and eukaryotic cells. In Saccharomyces cerevisiae, the nuclear/nucleolar 3′–5 …

The RNA exosome processes and degrades RNAs in archaeal and eukaryotic cells.
Exosomes from yeast and humans contain two active exoribonuclease components, Rrp6p …

The exosome consists of a core of ten essential proteins that includes the ribonuclease
Rrp44p and is present in both the cytoplasm and nucleus of eukaryotic cells. The …

Eukaryotic RNA exosomes participate in 3′ to 5′‐processing and degradation of RNA in
the nucleus and cytoplasm. RNA exosomes are multisubunit complexes composed of at …

Most RNAs in eukaryotic cells are produced as precursors that undergo processing at the
3′ and/or 5′ end to generate the mature transcript. In addition, many transcripts are …

The RNA exosome is an essential multisubunit ribonuclease (RNase) that contributes to
cytoplasmic and nuclear RNA decay and quality control. The 9-subunit exosome core (Exo9) …

The nuclear exosome, a macromolecular complex of 3′ to 5′ exonucleases, is required
for the post-transcriptional processing of a variety of RNAs including rRNAs and snoRNAs …

In yeast, the Trf4/5‐Air1/2‐Mtr4 polyadenylation (TRAMP) complex acts as a cofactor for the
nuclear exosome to promote degradation of various RNAs. However, the corresponding …

The exosome is a protein complex consisting of a variety of 3′-to-5′ exonucleases that
functions both in 3′-to-5′ trimming of rRNA precursors and in 3′-to-5′ degradation of …

The exosome ribonuclease complex functions in both the limited trimming of the 3′-ends of
nuclear substrates during RNA processing events and the complete destruction of nuclear …