Whole-genome DNA methylation profiling using MethylCap-seq
AB Brinkman, F Simmer, K Ma, A Kaan, J Zhu… - Methods, 2010 - Elsevier
MethylCap-seq is a robust procedure for genome-wide profiling of DNA methylation. The
approach consists of the capture of methylated DNA using the MBD domain of MeCP2, and …
approach consists of the capture of methylated DNA using the MBD domain of MeCP2, and …
Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping
Genomic DNA methylation profiles exhibit substantial variation within the human population,
with important functional implications for gene regulation. So far little is known about the …
with important functional implications for gene regulation. So far little is known about the …
Combining MeDIP-seq and MRE-seq to investigate genome-wide CpG methylation
DNA CpG methylation is a widespread epigenetic mark in high eukaryotes including
mammals. DNA methylation plays key roles in diverse biological processes such as X …
mammals. DNA methylation plays key roles in diverse biological processes such as X …
Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation
DNA methylation is an essential epigenetic modification that plays a key role associated with
the regulation of gene expression during differentiation, but in disease states such as …
the regulation of gene expression during differentiation, but in disease states such as …
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
Recent advancements in sequencing-based DNA methylation profiling methods provide an
unprecedented opportunity to map complete DNA methylomes. These include whole …
unprecedented opportunity to map complete DNA methylomes. These include whole …
Whole genome DNA methylation analysis based on high throughput sequencing technology
N Li, M Ye, Y Li, Z Yan, LM Butcher, J Sun, X Han… - Methods, 2010 - Elsevier
There are numerous approaches to decipher a whole genome DNA methylation profile
(“methylome”), each varying in cost, throughput and resolution. The gold standard of these …
(“methylome”), each varying in cost, throughput and resolution. The gold standard of these …
DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data
JM Gaspar, RP Hart - BMC bioinformatics, 2017 - Springer
Background DNA methylation is an epigenetic modification that is studied at a single-base
resolution with bisulfite treatment followed by high-throughput sequencing. After alignment …
resolution with bisulfite treatment followed by high-throughput sequencing. After alignment …
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
Quantitative comparison of genome-wide DNA methylation mapping technologies
DNA methylation plays a key role in regulating eukaryotic gene expression. Although
mitotically heritable and stable over time, patterns of DNA methylation frequently change in …
mitotically heritable and stable over time, patterns of DNA methylation frequently change in …
High resolution detection and analysis of CpG dinucleotides methylation using MBD-Seq technology
Methyl-CpG binding domain protein sequencing (MBD-seq) is widely used to survey DNA
methylation patterns. However, the optimal experimental parameters for MBD-seq remain …
methylation patterns. However, the optimal experimental parameters for MBD-seq remain …