[HTML][HTML] Renin-angiotensin system activation correlates with microvascular dysfunction in a prospective cohort study of clinical sepsis
KC Doerschug, AS Delsing, GA Schmidt, A Ashare - Critical Care, 2010 - Springer
Introduction Microvascular dysregulation characterized by hyporesponsive vessels and
heterogeneous bloodflow is implicated in the pathogenesis of organ failure in sepsis. The …
heterogeneous bloodflow is implicated in the pathogenesis of organ failure in sepsis. The …
[HTML][HTML] Myocardial effects of angiotensin II compared to norepinephrine in an animal model of septic shock
B Garcia, F Su, L Dewachter, R Favory, A Khaldi… - Critical Care, 2022 - Springer
Background Angiotensin II is one of the vasopressors available for use in septic shock.
However, its effects on the septic myocardium remain unclear. The aim of the study was to …
However, its effects on the septic myocardium remain unclear. The aim of the study was to …
[HTML][HTML] Angiotensin 1–7 in an experimental septic shock model
B Garcia, F Su, F Manicone, L Dewachter, R Favory… - Critical Care, 2023 - Springer
Background Alterations in the renin–angiotensin system have been implicated in the
pathophysiology of septic shock. In particular, angiotensin 1–7 (Ang-(1–7)), an anti …
pathophysiology of septic shock. In particular, angiotensin 1–7 (Ang-(1–7)), an anti …
[HTML][HTML] Angiotensin II in experimental hyperdynamic sepsis
Abstract Introduction Angiotensin II (Ang II) is a potential vasopressor treatment for
hypotensive hyperdynamic sepsis. However, unlike other vasopressors, its systemic …
hypotensive hyperdynamic sepsis. However, unlike other vasopressors, its systemic …
[HTML][HTML] A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome
A Khan, C Benthin, B Zeno, TE Albertson, J Boyd… - Critical care, 2017 - Springer
Background Renin-angiotensin system (RAS) signaling and angiotensin-converting enzyme
2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome …
2 (ACE2) have been implicated in the pathogenesis of acute respiratory distress syndrome …
[HTML][HTML] The effect of angiotensin II on blood pressure in patients with circulatory shock: a structured review of the literature
LW Busse, MT McCurdy, O Ali, A Hall, H Chen… - Critical Care, 2017 - Springer
Background Circulatory shock is a common syndrome with a high mortality and limited
therapeutic options. Despite its discovery and use in clinical and experimental settings more …
therapeutic options. Despite its discovery and use in clinical and experimental settings more …
[HTML][HTML] Acute kidney injury is associated with a decrease in cortical renal perfusion during septic shock
A Harrois, N Grillot, S Figueiredo, J Duranteau - Critical Care, 2018 - Springer
Background Renal perfusion status remains poorly studied at the bedside during septic
shock. We sought to measure cortical renal perfusion in patients with septic shock during …
shock. We sought to measure cortical renal perfusion in patients with septic shock during …
[HTML][HTML] Renal macro-and microcirculation autoregulatory capacity during early sepsis and norepinephrine infusion in rats
M Burban, JF Hamel, M Tabka, MR de La Bourdonnaye… - Critical Care, 2013 - Springer
Introduction The relationships between systemic hemodynamics and renal blood flow and
renal microcirculation are poorly known in sepsis. Norepinephrine (NE) infusion may add …
renal microcirculation are poorly known in sepsis. Norepinephrine (NE) infusion may add …
[HTML][HTML] ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock
DE Leisman, DR Handisides, LW Busse, MC Chappell… - Critical Care, 2024 - Springer
Background Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor
blockers (ARB) medications are widely prescribed. We sought to assess how pre-admission …
blockers (ARB) medications are widely prescribed. We sought to assess how pre-admission …
[HTML][HTML] Angiogenic factors and their soluble receptors predict organ dysfunction and mortality in post-cardiac arrest syndrome
T Wada, S Jesmin, S Gando, Y Yanagida, A Mizugaki… - Critical Care, 2012 - Springer
Introduction Post-cardiac arrest syndrome (PCAS) often leads to multiple organ dysfunction
syndrome (MODS) with a poor prognosis. Endothelial and leukocyte activation after whole …
syndrome (MODS) with a poor prognosis. Endothelial and leukocyte activation after whole …