Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions, including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …
H Kwon, JE Pessin - Frontiers in endocrinology, 2013 - frontiersin.org
For many years, adipose tissue was considered as an inert energy storage organ that accumulates and stores triacylglycerols during energy excess and releases fatty acids in …
N Ouchi, JL Parker, JJ Lugus, K Walsh - Nature reviews immunology, 2011 - nature.com
The worldwide epidemic of obesity has brought considerable attention to research aimed at understanding the biology of adipocytes (fat cells) and the events occurring in adipose …
P Trayhurn, IS Wood - Biochemical Society Transactions, 2005 - portlandpress.com
White adipose tissue (WAT) is a major endocrine and secretory organ, which releases a wide range of protein signals and factors termed adipokines. A number of adipokines …
K Nakamura, JJ Fuster, K Walsh - Journal of cardiology, 2014 - Elsevier
Obesity is a risk factor for various cardiovascular diseases including hypertension, atherosclerosis, and myocardial infarction. Recent studies aimed at understanding the …
H Cao - Journal of endocrinology, 2014 - joe.bioscientifica.com
The current global obesity pandemic is the leading cause for the soaring rates of metabolic diseases, especially diabetes, cardiovascular disease, hypertension, and non-alcoholic …
ZY Li, P Wang, CY Miao - Clinical and Experimental …, 2011 - Wiley Online Library
Obesity is a major determinant of cardiovascular disease (CVD). Studies in the past two decades have shown that adipose tissue is not merely an inert energy reserve of …
K Ohashi, R Shibata, T Murohara, N Ouchi - Trends in endocrinology & …, 2014 - cell.com
Obesity results in many health complications. Accumulating evidence indicates that the obese state is characterized by chronic low-grade inflammation, thereby leading to the …
T Kawai, MV Autieri, R Scalia - American Journal of …, 2021 - journals.physiology.org
Several lines of preclinical and clinical research have confirmed that chronic low-grade inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …