[PDF][PDF] Recent progresses on the metabolism modeling of Bacteria: definition of local and global modules and a first explanation of their emergence

V Fromion - ModellingComplex BiologicalSystems - webusers.i3s.unice.fr
Growth is a highly optimized process in bacteria since the battle for the conquest of
ecological niches is though. Understanding the key elements governing the growth rate …

Growth rate reflects a bottleneck on the resource sharing between cellular processes

A Goelzer, C Tanous-Healy, G Scorletti… - … : Systems Biology of …, 2010 - hal.science
The growth rate should be a highly optimized process in bacteria since the battle for the
conquest of ecological niches is tough. Understanding the main elements governing the …

Growth rate reflects a bottleneck on the resource sharing between cellular processes

G Scorletti - 2010 - agris.fao.org
The growth rate should be a highly optimized process in bacteria since the battle for the
conquest of ecological niches is tough. Understanding the main elements governing the …

Achieving optimal growth: lessons from simple metabolic modules

S Goyal, T Chen, N Wingreen - APS March Meeting …, 2009 - ui.adsabs.harvard.edu
Metabolism is a universal property of living organisms. While the metabolic network itself
has been well characterized, the logic of its regulation remains largely mysterious. Recent …

Growth efficiency as a cellular objective in Eschericia coli

T Aho, J Kesseli, O Yli-Harja, SA Kauffman - arXiv preprint arXiv …, 2012 - arxiv.org
The identification of cellular objectives is one of the central topics in the research of
microbial metabolic networks. In particular, the information about a cellular objective is …

A strategy to calculate the patterns of nutrient consumption by microorganisms applying a two-level optimisation principle to reconstructed metabolic networks

M Ponce de León, H Cancela, L Acerenza - Journal of biological physics, 2008 - Springer
Bacterial responses to environmental changes rely on a complex network of biochemical
reactions. The properties of the metabolic network determining these responses can be …

[PDF][PDF] evoDRUM: a new framework to model the evolution of metabolic networks under non-balanced growth conditions

G Grimaud - keynote talk by Ludovic Orlando, Pierre-Antoine … - hal.science
Mathematical modeling of evolution has been formalized in different frameworks, from
population genetics1 to quantitative genetics2 and evolutionary game theory3. Each of them …

Towards a systemic prediction of all cell component concentrations: the Resource Balance Analysis (RBA)

A Goelzer, C Tanous-Healy, G Scorletti, V Fromion - conférence: Bacell, 2009 - hal.science
Constraint-based approaches such as Flux Balance Analysis permit quantitative predictions
for the metabolic function during the exponential growth by integrating the stoichiometry of …

Towards a systemic prediction of all cell component concentrations: the Resource Balance Analysis (RBA)

G Scorletti - 2009 - agris.fao.org
Constraint-based approaches such as Flux Balance Analysis permit quantitative predictions
for the metabolic function during the exponential growth by integrating the stoichiometry of …

Identifying essential genes in Escherichia coli from a metabolic optimization principle

C Martelli, A De Martino, E Marinari… - Proceedings of the …, 2009 - National Acad Sciences
Understanding the organization of reaction fluxes in cellular metabolism from the
stoichiometry and the topology of the underlying biochemical network is a central issue in …