Protein acetylation has historically been considered a predominantly eukaryotic
phenomenon. Recent evidence, however, supports the hypothesis that acetylation broadly …

Acetylation is a posttranslational modification conserved in all domains of life that is carried
out by N-acetyltransferases. While acetylation can occur on N α-amino groups, this review …

ABSTRACT N ε-Lysine acetylation is now recognized as an abundant posttranslational
modification (PTM) that influences many essential biological pathways. Advancements in …

Post-translational modifications (PTM) decorate proteins to provide functional heterogeneity
to an existing proteome. The large number of known PTMs highlights the many ways that …

Protein acetylation is an evolutionarily conserved posttranslational modification. It affects
enzyme activity, metabolic flux distribution, and other critical physiological and biochemical …

Nε-acetylation is emerging as an abundant post-translational modification of bacterial
proteins. Two mechanisms have been identified: one is enzymatic, dependent on an …

Post-translational modification of proteins is a reversible mechanism of cellular adaptation to
changing environmental conditions. In eukaryotes, the physiological relevance of N-ɛ-lysine …

Protein acetylation plays a critical regulatory role in eukaryotes but until recently its
significance and function in bacteria and the archaea were obscure. It is now clear, however …

Protein acetylation is a universal post-translational modification which is found in both
eukaryotes and prokaryotes. This process is achieved enzymatically by the protein …

Lysine acetylation is a frequently occurring posttranslational modification in bacteria;
however, little is known about its origin and regulation. Using the model bacterium …