What is the efficacy of the RTS, S malaria vaccine?
CJA Duncan, AVS Hill - BMJ: British Medical Journal (Online), 2011 - search.proquest.com
RTS, S is thought to reduce the risk of infection from each exposure, rather than conferring"
all or nothing" protection on a proportion of recipients. 5 By this hypothesis, everyone …
all or nothing" protection on a proportion of recipients. 5 By this hypothesis, everyone …
The RTS, S/AS01 vaccine continues to show modest protection against malaria in African infants and children
PJ Rosenthal - BMJ Evidence-Based Medicine, 2015 - ebm.bmj.com
Methods In this phase III double-blind trial, 6537 infants (aged 6–12 weeks) and 8922
children (aged 5–17 months) were enrolled at 11 centres in seven countries, from 2009 to …
children (aged 5–17 months) were enrolled at 11 centres in seven countries, from 2009 to …
[PDF][PDF] RTS, S/AS01 malaria vaccine in African children
AV Hill - N Engl J Med, 2012 - core.ac.uk
To the Editor: In the article by the RTS, S Clinical Trials Partnership (Nov. 17 issue) 1 on the
phase 3 trial of RTS, S (ClinicalTrials. gov number, NCT00866619), an analysis of the …
phase 3 trial of RTS, S (ClinicalTrials. gov number, NCT00866619), an analysis of the …
Malaria vaccine difficult to roll out because four doses are needed, WHO says
A Gulland - 2015 - bmj.com
A phase III trial showed that the RTS, S vaccine, which acts against Plasmodium falciparum,
had an efficacy of around 30%. 1 The vaccine, which is most effective in children aged …
had an efficacy of around 30%. 1 The vaccine, which is most effective in children aged …
[HTML][HTML] The RTS, S malaria vaccine: Journey from conception to recommendation
OM Egbewande - Public Health in Practice, 2022 - Elsevier
The RTS, S malaria vaccine was recently recommended for use among children at risk in
malaria endemic regions. Although significant efforts have been made to minimise malaria …
malaria endemic regions. Although significant efforts have been made to minimise malaria …
Phase 3 trial with the RTS, S/AS01 malaria vaccine shows protection against clinical and severe malaria in infants and children in Africa
G Targett - BMJ Evidence-Based Medicine, 2015 - ebm.bmj.com
Methods This was a phase 3 double-blind trial of the RTS, S/AS01 vaccine which is directed
against the pre-erythrocytic stage of Plasmodium falciparum malaria. It was conducted in 11 …
against the pre-erythrocytic stage of Plasmodium falciparum malaria. It was conducted in 11 …
A vaccine against malaria: a substantial step forward
Two recent studies by Philip Bejon1 and Salim Abdulla, 2 and their respective colleagues,
represent an important step towards the development of a malaria vaccine that shows great …
represent an important step towards the development of a malaria vaccine that shows great …
Malaria vaccine becomes first to achieve 75% efficacy goal in trial of children
E Mahase - BMJ: British Medical Journal (Online), 2021 - search.proquest.com
A vaccine candidate for malaria has become the first to meet the World Health
Organization's 75% efficacy target, after a trial in 450 children reported 77% efficacy. 1 The …
Organization's 75% efficacy target, after a trial in 450 children reported 77% efficacy. 1 The …
Malaria vaccines for children: and now there are two
V Moorthy, MJ Hamel, PG Smith - The Lancet, 2024 - thelancet.com
In 2021, nearly half of the world's population lived at risk from malaria, with over 600 000
deaths annually, of which over 95% occur in the WHO African region and 80% of these in …
deaths annually, of which over 95% occur in the WHO African region and 80% of these in …
RTS, S/AS01 malaria vaccine and child mortality
P Aaby, A Rodrigues, PE Kofoed, CS Benn - The Lancet, 2015 - thelancet.com
RTS, S/AS01 malaria vaccination with and without a booster was associated with vaccine
efficacies (VE) against clinical malaria of 18–36%(July 4, p 31). 1 Modelling has estimated …
efficacies (VE) against clinical malaria of 18–36%(July 4, p 31). 1 Modelling has estimated …