TGFB1 disrupts the angiogenic potential of microvascular endothelial cells of the corpus luteum

D Maroni, JS Davis - Journal of cell science, 2011 - journals.biologists.com
Cyclical formation and regression of the ovarian corpus luteum is required for reproduction.
During luteal regression, the microvasculature of the corpus luteum is extensively disrupted …

Transforming growth factor Beta 1 stimulates profibrotic activities of luteal fibroblasts in cows

D Maroni, JS Davis - Biology of reproduction, 2012 - academic.oup.com
Luteolysis is characterized by angioregression, luteal cell apoptosis, and remodeling of the
extracellular matrix characterized by deposition of collagen 1. Transforming growth factor …

Thrombospondin-1 affects bovine luteal function via transforming growth factor-beta1-dependent and independent actions

S Farberov, R Meidan - Biology of Reproduction, 2016 - academic.oup.com
Abstract Thrombospondin-1 (THBS1) and transforming growth factor-beta1 (TGFB1) are
specifically up-regulated by prostaglandin F2alpha in mature corpus luteum (CL). This study …

[PDF][PDF] FGF2 is crucial for the development of bovine luteal endothelial networks in vitro

KJ Woad, AJ Hammond, M Hunter, GE Mann… - Reproduction, 2009 - Citeseer
The development of the corpus luteum requires angiogenesis, and involves the complex
interplay between factors such as vascular endothelial growth factor A (VEGFA), fibroblast …

[PDF][PDF] Fibroblast growth factor 2 is a key determinant of vascular sprouting during bovine luteal angiogenesis

KJ Woad, MG Hunter, GE Mann, M Laird… - …, 2012 - researchgate.net
Fibroblast growth factor (FGF) 2 and vascular endothelial growth factor (VEGF) A are thought
to be key controllers of luteal angiogenesis; however, their precise roles in the regulation …

Modulatory effects of TGF-β1 and BMP6 on thecal angiogenesis and steroidogenesis in the bovine ovary

D Mattar, M Samir, M Laird, PG Knight - Reproduction, 2020 - rep.bioscientifica.com
Angiogenesis plays an integral role in follicular and luteal development and is positively
regulated by several intra-ovarian factors including vascular endothelial growth factor A …

Fibroblast growth factor 2 induces the precocious development of endothelial cell networks in bovine luteinising follicular cells

M Laird, KJ Woad, MG Hunter, GE Mann… - Reproduction …, 2013 - CSIRO Publishing
The transition from follicle to corpus luteum represents a period of intense angiogenesis;
however, the exact roles of angiogenic factors during this time remain to be elucidated …

Regulation of angiogenesis-related prostaglandin f2alpha-induced genes in the bovine corpus luteum

Y Zalman, E Klipper, S Farberov, M Mondal… - Biology of …, 2012 - academic.oup.com
We recently compared prostaglandin F2alpha (PG)-induced global gene expression profiles
in PG-refractory, bovine corpus luteum (CL) collected on Day 4 of the estrous cycle, versus …

Luteal angiogenesis and its control

KJ Woad, RS Robinson - Theriogenology, 2016 - Elsevier
Angiogenesis, the formation of new blood vessels from preexisting ones, is critical to luteal
structure and function. In addition, it is a complex and tightly regulated process. Not only …

Potential role of follicle‐stimulating hormone (FSH) and transforming growth factor (TGFβ1) in the regulation of ovarian angiogenesis

SW Kuo, FC Ke, GD Chang, MT Lee… - Journal of Cellular …, 2011 - Wiley Online Library
Angiogenesis occurs during ovarian follicle development and luteinization. Pituitary
secreted FSH was reported to stimulate the expression of endothelial mitogen VEGF in …