The persistence of an active subventricular zone neural stem cell niche in the adult
mammalian forebrain supports its continued role in the production of new neurons and in …

Stem cells can exist in either active or quiescent states. In the aging hippocampus, adult
neural stem cells (aNSCs) shift into a quiescent state, contributing to age-related reductions …

Neurogenesis persists in the adult subventricular zone (SVZ) of the mammalian brain.
During aging, the SVZ neurogenic capacity undergoes a progressive decline, which is …

The mammalian brain is a remarkably complex organ comprising millions of neurons, glia
and various other cell types. Its impressive cytoarchitecture led to the long standing belief …

Neural stem cells (NSCs) persist in the adult mammalian brain through life. The
subventricular zone (SVZ) is the largest source of stem cells in the nervous system, and …

Neural stem cells (NSCs) critical for the continued production of new neurons and glia are
sequestered in distinct areas of the brain called stem cell niches. Until recently, only two …

In the adult mouse brain, the subventricular zone (SVZ) is a neurogenic stem cell niche only
4–5 cell diameters thick. Within this narrow zone, a unique microenvironment supports stem …

In the anterior forebrain, along the lateral wall of the lateral ventricles, a neurogenic stem cell
niche is found in a region referred to as the ventricular-subventricular zone (V-SVZ). In …

The adult mammalian brain retains neural stem cells that continually generate new neurons
within two restricted regions: the subventricular zone (SVZ) of the lateral ventricle and the …

The subventricular zone (SVZ) is a major germinal zone which persists in the adult brain.
The SVZ contains cells that self renew and continuously produce new neurons and glia. In …