Introduction: Traumatic spinal cord injury (SCI) causes severe and permanent functional
deficits, due to the primary mechanical insult, followed by secondary tissue degeneration …

Traumatic injury to the spinal cord results in multiple anatomical, physiological, and
functional deficits as a result of local neuronal and glial cell death as well as loss of …

Several lines of evidence suggest a biological role for peroxisome proliferator-activated
receptor (PPAR)-β/δ in the pathogenesis many diseases. The aim of the present study was …

Traumatic spinal cord injury (SCI) is accompanied by a dramatic inflammatory response,
which escalates over the first week post-injury and is thought to contribute to secondary …

Traumatic injury or disease of the spinal cord and brain elicits multiple cellular and
biochemical reactions that together cause or are associated with neuropathology …

Peroxisome proliferator-activated receptors [PPARs; PPARα, PPARβ/δ (also known as
PPARδ), and PPARγ] widely recognized for their important role in glucose/lipid homeostasis …

The peroxisome proliferator-activated receptor-α (PPAR-α) is a member of the nuclear
receptor superfamily of ligand-dependent transcription factors related to retinoid, steroid …

Peroxisome proliferator-activated receptor gamma (PPARγ) has been implicated in the
pathology of numerous diseases involving diabetes, stroke, cancer, or obesity. It is …

PPARs (peroxisome-proliferator-activated receptors) are ligand-activated transcriptional
factor receptors belonging to the so-called nuclear receptor family. The three isoforms of …

Spinal cord injury (SCI) results in the loss of function below the lesion. Secondary injury
following the primary impact includes a number of biochemical and cellular alterations …