The RTS, S malaria vaccine

CJM Whitty - Bmj, 2011 - bmj.com
The initial results of the phase III clinical trial for RTS, S—currently the leading malaria
vaccine candidate—were recently announced, 1 amid international media coverage …

Malaria vaccine difficult to roll out because four doses are needed, WHO says

A Gulland - 2015 - bmj.com
A phase III trial showed that the RTS, S vaccine, which acts against Plasmodium falciparum,
had an efficacy of around 30%. 1 The vaccine, which is most effective in children aged …

WHO hails “historic day” as it recommends malaria vaccine

J Wise - 2021 - bmj.com
The World Health Organization has recommended widespread use of the RTS, S malaria
vaccine among children in sub-Saharan Africa and other areas with moderate to high …

Malaria vaccine trial shows lower efficacy in younger than in older infants

A Gulland - 2012 - bmj.com
The efficacy of the vaccine RTS, S/AS01 in infants aged 6-12 weeks against clinical and
severe malaria was 31% and 37%, respectively, found the study, published in the New …

What is the efficacy of the RTS, S malaria vaccine?

CJA Duncan, AVS Hill - BMJ: British Medical Journal (Online), 2011 - search.proquest.com
RTS, S is thought to reduce the risk of infection from each exposure, rather than conferring"
all or nothing" protection on a proportion of recipients. 5 By this hypothesis, everyone …

Malaria vaccine is partly effective in young children, study shows

S Mayor - BMJ, 2015 - bmj.com
The study included 6537 infants aged 6-12 weeks and 8922 children aged 5-17 months who
were enrolled at 11 centres in seven countries across sub-Saharan Africa. They were …

Candidate malaria vaccine becomes less effective over time, study shows

J Wise - BMJ, 2013 - bmj.com
A candidate vaccine against malaria has been shown to almost halve the number of malaria
cases in young children but only to reduce cases by a quarter in infants. The effectiveness of …

Trial starts of malaria vaccine in 2000 children in Mozambique

A Gulland - BMJ, 2003 - bmj.com
Pedro Alonso, head of the Centre for International Health at the University of Barcelona,
Spain, and principal investigator of the vaccine trial, told a press conference earlier this …

Promise of new malaria vaccines

PJ Hotez, M Matshaba - bmj, 2022 - bmj.com
Throughout the covid-19 pandemic, global health scientists and professionals worried not
only about this new and emerging viral infection but also about a potential diversion of …

WHO recommends second vaccine for malaria prevention in children

E Mahase - 2023 - bmj.com
“This second vaccine holds real potential to close the huge demand-and-supply gap,” said
WHO's regional director for Africa, Matshidiso Moeti.“Delivered to scale and rolled out …