This thesis is divided into two parts, assessing marine and synthetic compounds active firstly
against Plasmodium falciparum (Chapter 3 and 4) and secondly active against methicillin …

Over a decade ago Wright et al., proposed a putative antiplasmodial mechanism of action for
marine isonitriles (1, and 3–6) and isothiocyanate (2) that involved interference in heme …

8β, 13β-Dihydroxypodocarpane and eight C-13 substituted derivatives were prepared from
the precursor 8β-hydroxy-13-podocarpanone synthesised from the naturally occurring …

This review highlights recently discovered antimalarial natural products from marine and
freshwater sources described in the literature from 2006 to 2008. The structures as well as …

Resistance of plasmodia parasites, Cryptococcus neoformans and methicillin resistant
Staphylococcus aureus to the available medications are a major cause of concern …

Screening of synthesized and isolated marine natural products for in vitro activity against
four parasitic protozoa identified the ascidian metabolites orthidine F (1), didemnidine B (2) …

Screening of synthesized and isolated marine natural products for in vitro activity against
four parasitic protozoa has identified the ascidian metabolite 1, 14 …

In the course of a medium throughput screen of 640 plant extracts for antimalarial activity an
ethyl acetate extract of Pistacia atlantica DC.(Anacardiaceae) was found to be active. With …

Syncarpamide 1, a norepinephrine alkaloid isolated from the leaves of Zanthoxylum
syncarpum (Rutaceae) exhibited promising antiplasmodial activities against Plasmodium …

In this short review, an approach to the isolation of potential antimalarial agents and lead
compounds is outlined. A discussion of organism collection, followed by a description of …