Cannabinoids as potential new therapeutics of gastrointestinal motility and inflammatory disorders

L Roberts - 2011 - orca.cardiff.ac.uk
Cannabinoids show potential as new treatments for inflammatory bowel disease (IBD),
exerting several favourable effects in the gut, including anti-inflammatory and …

[HTML][HTML] Involvement of the cannabinoid system in chronic inflammatory intestinal diseases: opportunities for new therapies

PA Lima, BB Berg, MGM e Castor - Intestinal research, 2022 - synapse.koreamed.org
The components of the endogenous cannabinoid system are widely expressed in the
gastrointestinal tract contributing to local homeostasis. In general, cannabinoids exert …

[PDF][PDF] page: Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl) methanone (SAB378), a peripherally restricted, cannabinoid CB1/CB2 receptor agonist inhibits …

NL Cluny, CM Keenan, M Duncan, A Fox, B Lutz… - 2010 - Citeseer
The endocannabinoid system is involved in the regulation of gastrointestinal (GI) motility and
inflammation. Using the peripherally restricted, cannabinoid CB1/CB2 receptor agonist …

Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl) methanone (SAB378), a peripherally restricted cannabinoid CB1/CB2 receptor agonist, inhibits gastrointestinal motility …

NL Cluny, CM Keenan, M Duncan, A Fox, B Lutz… - … of Pharmacology and …, 2010 - ASPET
The endocannabinoid system is involved in the regulation of gastrointestinal (GI) motility and
inflammation. Using the peripherally restricted cannabinoid (CB) 1/CB2 receptor agonist …

Cannabinoids as gastrointestinal anti‐inflammatory drugs

A Fabisiak, J Fichna - Neurogastroenterology & Motility, 2017 - Wiley Online Library
In this mini‐review, we focus on the potential of the endocannabinoid system as a target for
novel therapies to treat gastrointestinal (GI) inflammation. We discuss the organization of the …

Cannabinoid CB1‐receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation

AA Izzo, F Fezza, R Capasso, T Bisogno… - British journal of …, 2001 - Wiley Online Library
We have studied the effect of cannabinoid agonists (CP 55,940 and cannabinol) on
intestinal motility in a model of intestinal inflammation (induced by oral croton oil in mice) …

Cannabinoids and gastrointestinal motility: pharmacology, clinical effects, and potential therapeutics in humans

M Camilleri - Neurogastroenterology & Motility, 2018 - Wiley Online Library
Background Cannabinoid agents and cannabis are frequently used for relief of diverse
gastrointestinal symptoms. Purpose The objective of this article is to increase the awareness …

Cannabinoids and intestinal motility: welcome to CB2 receptors

AA Izzo - British journal of pharmacology, 2004 - Wiley Online Library
Δ9‐Tetrahydrocannabinol (the active ingredient of marijuana), as well as endogenous and
synthetic cannabinoids, exert many biological functions by activating two types of …

Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases

R Schicho, M Storr - Canadian Journal of Gastroenterology and …, 2011 - Wiley Online Library
Many beneficial effects of herbal and synthetic cannabinoids on gut motility and
inflammation have been demonstrated, suggesting a vast potential for these compounds in …

[PDF][PDF] The synthetic cannabinoid agonist, WIN55, 212-2, inhibits jejunal afferent responses to LPS in a cannabinoid-receptor independent manner

J Donovan, D Grundy - Gastroenterology, 2009 - academia.edu
Cannabinoids have been shown to exert anti-inflammatory and anti-nociceptive functions in
many models of human disease. We recently provided evidence that the synthetic …