At present, secretin and its receptor have only been identified in mammals, and the origin of
this ligand-receptor pair in early vertebrates is unclear. In addition, the elusive similarities of …

In mammals, secretin is a 27-amino acid peptide that was first studied in 1902 by Bayliss
and Starling from the extracts of the jejunal mucosa for its ability to stimulate pancreatic …

In mammals, secretin is a 27-amino acid peptide that was first studied in 1902 by Bayliss
and Starling from the extracts of the jejunal mucosa for its ability to stimulate pancreatic …

Twenty-one members of the secretin family (family 2) of G-protein-coupled receptors
(GPCRs) were identified via directed cloning and data-mining of the Fugu Genome …

Background The secretin family is a pleotropic group of brain-gut peptides with affinity for
class 2 G-protein coupled receptors (secretin family GPCRs) proposed to have emerged …

The secretin receptor (SCTR) is a member of Class 2 subfamily B1 GPCRs and part of the
PAC 1/VPAC receptor subfamily. This receptor has long been known in mammals but has …

Lungfishes are currently considered the closest living relatives of tetrapods and represent an
interesting group for the study of evolutionary traits in the transition from fishes to tetrapods …

Abstract Secretoneurin, a 33–34 amino acid neuropeptide derived from the proteolytic
processing of the secretogranin‐II precursor protein, is reasonably well conserved in …

Although recently discovered, orexins have been rapidly established as important
neuropeptides in regulating physiological processes including food intake, sleep/wake …

Orexins A (ox A) and B are two peptides originally discovered in neurons of rat
hypothalamus, and later found in different cellular types of the gastrointestinal and genital …