The functional role of secretin outside the gastrointestinal system has been a mystery to
endocrinologists for many years. With the availability of secretin‐and secretin receptor …

Secretin is a polypeptide hormone initially identified for its gastrointestinal functions.
However, emerging evidences show wide distribution of secretin and secretin receptor …

The discovery of secretin initiated the field of endocrinology. Over the past century, multiple
gastrointestinal functions of secretin have been extensively studied, and it was discovered …

Secretin holds a unique place in the history of endocrinology and gastrointestinal
physiology, as it is the first peptide designated as a hormone. During the last century since …

Since its initial discovery, secretin is now coined as a classical hormone with widespread
distribution. In particular, numerous studies have demonstrated the abundant expression of …

Secretin is a gut peptide hormone that is also expressed in the CNS. To explore the potential
neuroactive role of secretin in the brain, we have generated secretin deficient mice. Secretin …

Secretin is a classical gastrointestinal peptide while its neuroactive functions in the central
nervous system have recently been consolidated. In the past, there was little information …

The role of secretin as a classical hormone in the gastrointestinal system is well-established.
The recent debate on the use of secretin as a potential therapeutic treatment for autistic …

Secretin shows a wide distribution in the brain. Functional significance of central secretin is
stressed since it has been associated with autism and schizophrenia. The presence of the …

Secretin, a 27-amino acid gastrointestinal peptide, was initially discovered based on its
activities in stimulating pancreatic juice. In the past 20 years, secretin was demonstrated to …