Shape change in the receptor for gliding motility in Plasmodium sporozoites
G Song, AC Koksal, C Lu… - Proceedings of the …, 2012 - National Acad Sciences
Sporozoite gliding motility and invasion of mosquito and vertebrate host cells in malaria is
mediated by thrombospondin repeat anonymous protein (TRAP). Tandem von Willebrand …
mediated by thrombospondin repeat anonymous protein (TRAP). Tandem von Willebrand …
Experimentally induced blood stage malaria infection as a tool for clinical research
A system for experimentally induced blood stage malaria infection (IBSM) with Plasmodium
falciparum by direct intravenous inoculation of infected erythrocytes was developed at the …
falciparum by direct intravenous inoculation of infected erythrocytes was developed at the …
Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection
Malaria is a vector-borne infectious disease caused by infection with eukaryotic pathogens
termed Plasmodium. Epidemiological hallmarks of Plasmodium falciparum malaria are …
termed Plasmodium. Epidemiological hallmarks of Plasmodium falciparum malaria are …
Phase 1 Study in Malaria Naïve Adults of BSAM2/Alhydrogel®+CPG 7909, a Blood Stage Vaccine against P. falciparum Malaria
RD Ellis, Y Wu, LB Martin, D Shaffer, K Miura, J Aebig… - 2012 - journals.plos.org
A Phase 1 dose escalating study was conducted in malaria naïve adults to assess the safety,
reactogenicity, and immunogenicity of the blood stage malaria vaccine …
reactogenicity, and immunogenicity of the blood stage malaria vaccine …
Genetic engineering of attenuated malaria parasites for vaccination
Vaccination with live-attenuated Plasmodium sporozoites that arrest in the liver can
completely protect against a malaria infection both in animal models and in humans; this has …
completely protect against a malaria infection both in animal models and in humans; this has …
Genetic Variation in the Plasmodium falciparum Circumsporozoite Protein in India and Its Relevance to RTS,S Malaria Vaccine
RTS, S is the most advanced malaria vaccine candidate, currently under phase-III clinical
trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region …
trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region …
New Trifluoromethyl Triazolopyrimidines as Anti-Plasmodiumfalciparum Agents
N Boechat, LCS Pinheiro, TS Silva, ACC Aguiar… - Molecules, 2012 - mdpi.com
According to the World Health Organization, half of the World's population, approximately
3.3 billion people, is at risk for developing malaria. Nearly 700,000 deaths each year are …
3.3 billion people, is at risk for developing malaria. Nearly 700,000 deaths each year are …
Whole parasite vaccination approaches for prevention of malaria infection
Malaria is caused by complex protozoan Plasmodium parasites that have foiled efforts to
develop a protective vaccine. Despite this, it has been known for more than 40 years that …
develop a protective vaccine. Despite this, it has been known for more than 40 years that …
Agrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas disease
M Witschel, M Rottmann, M Kaiser… - PLoS neglected tropical …, 2012 - journals.plos.org
In tropical regions, protozoan parasites can cause severe diseases with malaria,
leishmaniasis, sleeping sickness, and Chagas disease standing in the forefront. Many of the …
leishmaniasis, sleeping sickness, and Chagas disease standing in the forefront. Many of the …
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy.
Evolutionary theorists have raised the possibility that some types of vaccine could also …
Evolutionary theorists have raised the possibility that some types of vaccine could also …