Plasmodium falciparum Line-Dependent Association of In Vitro Growth-Inhibitory Activity and Risk of Malaria

J Rono, A Färnert, D Olsson, F Osier, I Rooth… - Infection and …, 2012 - Am Soc Microbiol
Plasmodium falciparum's ability to invade erythrocytes is essential for its survival within the
human host. Immune mechanisms that impair this ability are therefore expected to contribute …

[HTML][HTML] Decision-making on malaria vaccine introduction: the role of cost-effectiveness analyses

VS Moorthy, R Hutubessy… - Bulletin of the World …, 2012 - SciELO Public Health
• What is the evidence that RTS, S/AS01 vaccination is not associated with serious adverse
reactions in children aged less than 17 months?• What level of protection against clinical …

[PDF][PDF] Immunogenicity of recombinant BCG-based vaccine expressing the 22 kDa of serine repeat antigen (SE22) of Plasmodium falciparum

WH Teo, AA Nurul, MN Norazmi - Trop Biomed, 2012 - msptm.org
The Plasmodium falciparum serine repeat antigen (SERA) is one of the promising blood-
stage malarial vaccine candidates. In this study, recombinant Mycobacterium bovis bacille …

Towards the development of a fully protective Plasmodium falciparum antimalarial vaccine

ME Patarroyo, A Bermudez… - Expert Review of …, 2012 - Taylor & Francis
If ever there were a truism then it would be that a completely protective Plasmodium
falciparum malaria vaccine is desperately needed. Our institute has devoted all its efforts …

Practical issues in relation to clinical trials in children in low-income countries: experience from the front line

E Molyneux, D Mathanga, D Witte… - Archives of disease in …, 2012 - adc.bmj.com
Clinical trials in children in resource-poor environments are essential for local health policy
and practice to be relevant and evidence based. Research must be ethical, appropriate …

Country planning for health interventions under development: lessons from the malaria vaccine decision-making framework and implications for other new …

A Brooks, A Ba-Nguz - Health Policy and Planning, 2012 - academic.oup.com
Traditionally it has taken years or decades for new public health interventions targeting
diseases found in developing countries to be accessible to those most in need. One reason …

[HTML][HTML] Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and adenovirus (Ad5) immune mice

NJ Schuldt, YA Aldhamen, S Godbehere-Roosa… - Malaria Journal, 2012 - Springer
Background Induction of potent long lasting effector T cell responses against liver stage
malaria antigens strongly correlates with protection from malaria. While Adenovirus serotype …

[HTML][HTML] Risque palustre: appréhender la vulnérabilité des individus à l'échelle locale (Sud du Bénin)

C Pierrat - VertigO-la revue électronique en sciences de l' …, 2012 - journals.openedition.org
Le paludisme représente aujourd'hui l'une des pandémies les plus meurtrières des pays du
Sud, la majorité de la population à risque se trouvant en Afrique sub-saharienne. C'est une …

Plasmodium falciparum malaria vaccines: current status, pitfalls and future directions

A Salvador, RM Hernández, JL Pedraz… - Expert review of …, 2012 - Taylor & Francis
Currently, a vaccine against malaria has not yet been licensed. Different approaches have
been explored with different immune responses, but neither has fulfilled the criteria for being …

Immunomodulatory effects of antimicrobial agents. Part II: antiparasitic and antifungal agents

MT Labro - Expert review of anti-infective therapy, 2012 - Taylor & Francis
Antiparasitic and antifungal drugs have not received the same high level of recognition as
antimicrobial drugs. They are comparatively few in number, the great majority of them were …