Secretin and its receptors show wide distribution in the central nervous system. It was
demonstrated previously that intravenous (iv) and intracerebroventricular (icv) application of …

It was previously demonstrated that secretin influenced the behavior of rats investigated by
open-field test. In the present experiment, we have compared the effect of …

The effect of secretin on behavioral and physiological functions in the rat was investigated.
Secretin injected intracerebroventricularly (ICV) significantly increased defecation and …

Secretin shows a wide distribution in the brain. Functional significance of central secretin is
stressed since it has been associated with autism and schizophrenia. The presence of the …

The release and physiological actions of secretin on pancreatic exocrine secretion and
gastric secretion of acid and motility are regulated by neuro-hormonal control. The release of …

Although the existence of the receptor for secretin in the brain was suggested, the
localization of secretin receptor and the neuronal function of secretin have not been clarified …

The expression and spatial distribution of secretin and its receptor in human cerebellum
were investigated by in situ hybridization and immunohistochemical techniques. Secretin …

The binding of [125I] secretin to rat brain membranes was investigated. Radiolabeled
secretin bound with high affinity (KD= 0.2 nM) to a single class of noninteracting sites …

Immunocytochemistry and in situ hybridization revealed abundant secretin expressing cells
on duodenal villi with a gradual decrease throughout the small intestines of the rat. They …

For the first time, the relationship between secretin and autism has been demonstrated by
one of us. Intravenous administration of secretin in autistic children caused a fivefold higher …