The overproduction of reactive oxygen species and the resulting damage are central to the
pathology of many diseases. The study of the temporal and spatial accumulation of reactive …

We have recently described an optimised electrode for the detection of enzymatic and
cellular superoxide (O2•−) production based on cytochrome c immobilized covalently at a …

Direct real-time electrochemical measurements have offered new insight into the importance
of free radical interplay in a number of cell culture and in vivo models of neurodegenerative …

A cytochrome c-coated platinized carbon electrode was utilized to detect superoxide
generated by the brain during hypoxia/hypercarbia, focal ischemia, and reperfusion and …

A novel multilayer cytochrome c electrode for the quantification of superoxide radical
concentrations is introduced. The electrode consists of alternating layers of cytochrome c …

Superoxide radicals are of great interest in several fields of biochemical research. The
univalent reduction of oxygen leads to the superoxide anion, which has both oxidizing and …

A superoxide sensor based on immobilized cytochrome c has been applied for short time
implantation. It has a “stabilization time” of several minutes and the working stability during …

Effective monitoring of cerebral ascorbate following intravenous antioxidant treatment is of
great importance in evaluating the antioxidant efficiency for neuroprotection because …

The dynamics of superoxide anion (O2−) in vivo remain to be clarified because no
appropriate method exists to directly and continuously monitor and evaluate O2− in vivo …

The superoxide radical anion (SO) is a critical biomarker for monitoring cellular stress
responses. Electrochemical SO biosensors are frequently constructed through the covalent …