Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children
T Lavstsen, L Turner, F Saguti… - Proceedings of the …, 2012 - National Acad Sciences
The clinical outcome of Plasmodium falciparum infections ranges from asymptomatic
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
parasitemia to severe malaria syndromes associated with high mortality. The virulence of P …
Virulence of Malaria Is Associated with Differential Expression of Plasmodium falciparum var Gene Subgroups in a Case-Control Study
M Kaestli, IA Cockburn, A Cortés, K Baea… - The Journal of …, 2006 - academic.oup.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a major pathogenicity
factor in falciparum malaria that mediates cytoadherence. PfEMP1 is encoded by∼ 60 var …
factor in falciparum malaria that mediates cytoadherence. PfEMP1 is encoded by∼ 60 var …
Malaria's deadly grip: cytoadhesion of Plasmodium falciparum‐infected erythrocytes
Cytoadhesion of P lasmodium falciparum‐infected erythrocytes to host microvasculature is a
key virulence determinant. Parasite binding is mediated by a large family of clonally variant …
key virulence determinant. Parasite binding is mediated by a large family of clonally variant …
Differential Expression of var Gene Groups Is Associated with Morbidity Caused by Plasmodium falciparum Infection in Tanzanian Children
M Rottmann, T Lavstsen, JP Mugasa… - Infection and …, 2006 - Am Soc Microbiol
The var gene family of Plasmodium falciparum encodes the variant surface antigen
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 is considered …
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1). PfEMP1 is considered …
PfEMP1-DBL1α amino acid motifs in severe disease states of Plasmodium falciparum malaria
An infection with Plasmodium falciparum may lead to severe malaria as a result of excessive
binding of infected erythrocytes in the microvasculature. Vascular adhesion is mediated by …
binding of infected erythrocytes in the microvasculature. Vascular adhesion is mediated by …
[HTML][HTML] Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia
HM Kyriacou, GN Stone, RJ Challis, A Raza… - Molecular and …, 2006 - Elsevier
The Plasmodium falciparum variant erythrocyte surface antigens known as PfEMP1,
encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis …
encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis …
Identification of a Conserved Plasmodium falciparum var Gene Implicated in Malaria in Pregnancy
JA Rowe, SA Kyes, SJ Rogerson… - The Journal of …, 2002 - academic.oup.com
The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family is a highly
polymorphic class of variant surface antigens encoded by var genes that play an important …
polymorphic class of variant surface antigens encoded by var genes that play an important …
[HTML][HTML] Expression of the Domain Cassette 8 Plasmodium falciparum Erythrocyte Membrane Protein 1 Is Associated with Cerebral Malaria in Benin
Background Plasmodium falciparum erythrocyte membrane protein-1 (Pf EMP-1) is a highly
polymorphic adherence receptor expressed on the surface of infected erythrocytes. Based …
polymorphic adherence receptor expressed on the surface of infected erythrocytes. Based …
Plasmodium falciparum var gene expression is modified by host immunity
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a potentially important
family of immune targets, which play a central role in the host–parasite interaction by binding …
family of immune targets, which play a central role in the host–parasite interaction by binding …
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains
The binding of erythrocytes infected with mature blood stage parasites to the vascular bed is
key to the pathogenesis of malignant malaria. The binding is mediated by members of …
key to the pathogenesis of malignant malaria. The binding is mediated by members of …