Investigations of oxidative stress effects and their mechanisms in rat brain after systemic administration of ceria engineered nanomaterials
SS Hardas - 2012 - uknowledge.uky.edu
Advancing applications of engineered nanomaterials (ENM) in various fields create the
opportunity for intended (eg drug and gene delivery) or unintended (eg occupational and …
opportunity for intended (eg drug and gene delivery) or unintended (eg occupational and …
Rat hippocampal responses up to 90 days after a single nanoceria dose extends a hierarchical oxidative stress model for nanoparticle toxicity
SS Hardas, R Sultana, G Warrier, M Dan, P Wu… - …, 2014 - Taylor & Francis
Ceria engineered nanomaterials (ENMs) have very promising commercial and therapeutic
applications. Few reports address the effects of nanoceria in intact mammals, let alone long …
applications. Few reports address the effects of nanoceria in intact mammals, let alone long …
Rat brain pro-oxidant effects of peripherally administered 5 nm ceria 30 days after exposure
SS Hardas, R Sultana, G Warrier, M Dan, RL Florence… - Neurotoxicology, 2012 - Elsevier
The objective of this study was to determine the residual pro-or anti-oxidant effects in rat
brain 30 days after systemic administration of a 5nm citrate-stabilized ceria dispersion. A∼ …
brain 30 days after systemic administration of a 5nm citrate-stabilized ceria dispersion. A∼ …
Biodistribution and oxidative stress effects of a systemically-introduced commercial ceria engineered nanomaterial
The objective was to characterize the biodistribution of nanoscale ceria from blood and its
effects on oxidative stress endpoints. A commercial 5% crystalline ceria dispersion in water …
effects on oxidative stress endpoints. A commercial 5% crystalline ceria dispersion in water …
Brain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceria
SS Hardas, DA Butterfield, R Sultana… - Toxicological …, 2010 - academic.oup.com
Engineered nanoscale ceria is used as a diesel fuel catalyst. Little is known about its
mammalian central nervous system effects. The objective of this paper is to characterize the …
mammalian central nervous system effects. The objective of this paper is to characterize the …
Bio‐distribution and in vivo antioxidant effects of cerium oxide nanoparticles in mice
Cerium oxide nanoparticles have oxygen defects in their lattice structure that enables them
to act as a regenerative free radical scavenger in a physiological environment. We …
to act as a regenerative free radical scavenger in a physiological environment. We …
Neuron and Glial Cells Exposed to Cerium Dioxide Nanoparticles: Results from MTT and γH2AX Assays
N Fernández-Bertólez, A Touzani, L Martínez… - Materials …, 2023 - mdpi.com
Cerium dioxide nanoparticles (CeO2NP) show antioxidant enzyme-like properties and
reactive oxygen species (ROS) scavenging activity, making them a promising material for …
reactive oxygen species (ROS) scavenging activity, making them a promising material for …
Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats
Nanoceria is used as a catalyst in diesel fuel, as an abrasive in printed circuit manufacture,
and is being pursued as an antioxidant therapeutic. Our objective is to extend previous …
and is being pursued as an antioxidant therapeutic. Our objective is to extend previous …
Toxicity and protective effects of cerium oxide nanoparticles (nanoceria) depending on their preparation method, particle size, cell type, and exposure route
J Gagnon, KM Fromm - European Journal of Inorganic …, 2015 - Wiley Online Library
Nanoceria (cerium oxide nanoparticles) toxicity is currently a concern because of its use in
motor vehicles in order to reduce carbon monoxide (CO), nitrogen oxides (NOx), and …
motor vehicles in order to reduce carbon monoxide (CO), nitrogen oxides (NOx), and …
Behavioral, biochemical, histopathological evaluation and gene expression of brain injury induced by nanoceria injected intranasal or intraperitoneal in mice
Background Nanotechnology has shown a remarkable progress nevertheless, there is a
growing concern about probable neurotoxic and neurodegenerative effects due to NPs …
growing concern about probable neurotoxic and neurodegenerative effects due to NPs …