Adverse childhood experiences are associated with migraine and vascular biomarkers

GE Tietjen, J Khubchandani… - … : The Journal of Head …, 2012 - Wiley Online Library
Objectives.—Migraine is a risk factor for stroke in young women. Biomarker studies implicate
endothelial activation as a possible mechanism. Emerging relationships of childhood …

Migraine and biomarkers of endothelial activation in young women

GE Tietjen, NA Herial, L White, C Utley, JM Kosmyna… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—There is mounting evidence of endothelial activation and
dysfunction in migraine. Our objectives were to determine in a population of premenopausal …

Adverse childhood experiences (ACEs) and headaches among children: a cross‐sectional analysis

F Mansuri, MC Nash, C Bakour… - Headache: The Journal of …, 2020 - Wiley Online Library
Objectives This cross‐sectional study examined the association between adverse childhood
experiences (ACEs) and history of frequent headaches (including migraine) among children …

Vascular risk in migraineurs: interaction of endothelial and cortical excitability factors

N Murinova, DL Krashin, S Lucas - Headache: The Journal of …, 2014 - Wiley Online Library
Background Migraine is a common primary headache disorder occurring predominantly in a
young, relatively healthy population. Results There is a growing literature on associations …

Migraine and vascular disease biomarkers: a population-based case-control study

GE Tietjen, J Khubchandani, N Herial… - …, 2018 - journals.sagepub.com
Background The underpinnings of the migraine-stroke association remain uncertain, but
endothelial activation is a potential mechanism. We evaluated the association of migraine …

Adverse childhood experiences and frequent headaches in adults

R Anda, G Tietjen, E Schulman… - … : The Journal of Head …, 2010 - Wiley Online Library
Background.—A variety of studies have linked childhood maltreatment to headaches,
including migraines, and to headache severity. This study assesses the relationship of …

Early life stress in adolescent migraine and the mediational influence of symptoms of depression and anxiety in a Canadian cohort

NG Hammond, SL Orr, I Colman - Headache: The Journal of …, 2019 - Wiley Online Library
Objective This study sought to examine the association between early life stressors and
adolescent headache in the Canadian population, and the potential mediating influence of …

Adverse childhood experiences and primary headache disorders: a systematic review, meta-analysis, and application of a biological theory

C Sikorski, AC Mavromanoli, K Manji, D Behzad… - Neurology, 2023 - AAN Enterprises
Background and Objectives Headache disorders are among the leading causes of disability
worldwide. While an association between adverse childhood experiences and primary …

The painful legacy of childhood violence: migraine headaches among adult survivors of adverse childhood experiences

S Brennenstuhl… - Headache: The Journal of …, 2015 - Wiley Online Library
Background Childhood adversities have been associated with adult migraine in the general
population. However, most research has focused on only a few types of maltreatment and …

Headache and biomarkers predictive of vascular disease in a representative sample of US children

KB Nelson, AK Richardson, J He… - … of pediatrics & …, 2010 - jamanetwork.com
Objective To examine the association of childhood headache disorders with markers of risk
for cardiovascular and cerebrovascular disease. Design Information was collected on …