Protective effects of flavanol-rich dark chocolate on endothelial function and wave reflection during acute hyperglycemia

D Grassi, G Desideri, S Necozione, F Ruggieri… - …, 2012 - Am Heart Assoc
Nitric oxide plays a pivotal role in regulating vascular tone. Different studies show
endothelial function is impaired during hyperglycemia. Dark chocolate increases flow …

Effect of dark chocolate on arterial function in healthy individuals: cocoa instead of ambrosia?

C Vlachopoulos, N Alexopoulos… - Current hypertension …, 2006 - Springer
Cocoa has been consumed for at least 2500 years, and for long time it has been regarded
as a medicine. Arterial function is of paramount importance for the proper function and …

Protective effects of dark chocolate on endothelial function and diabetes

D Grassi, G Desideri, C Ferri - Current Opinion in Clinical Nutrition …, 2013 - journals.lww.com
The endothelium plays a pivotal role in the arterial homeostasis, and insulin resistance is the
most important pathophysiological feature in various prediabetic and diabetic states …

[HTML][HTML] Blood Pressure Is Reduced and Insulin Sensitivity Increased in Glucose-Intolerant, Hypertensive Subjects after 15 Days of Consuming High-Polyphenol Dark …

D Grassi, G Desideri, S Necozione, C Lippi… - The Journal of …, 2008 - Elsevier
Flavanols from chocolate appear to increase nitric oxide bioavailability, protect vascular
endothelium, and decrease cardiovascular disease (CVD) risk factors. We sought to test the …

Cocoa reduces blood pressure and insulin resistance and improves endothelium-dependent vasodilation in hypertensives

D Grassi, S Necozione, C Lippi, G Croce, L Valeri… - …, 2005 - Am Heart Assoc
Consumption of flavanol-rich dark chocolate (DC) has been shown to decrease blood
pressure (BP) and insulin resistance in healthy subjects, suggesting similar benefits in …

Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans

NDL Fisher, M Hughes, M Gerhard-Herman… - Journal of …, 2003 - journals.lww.com
Background Consumption of flavonoid-rich beverages, including tea and red wine, has been
associated with a reduction in coronary events, but the physiological mechanism remains …

Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men

D Esser, M Mars, E Oosterink, A Stalmach… - The FASEB …, 2014 - Wiley Online Library
Flavanol‐enriched chocolate consumption increases endothelium‐dependent vasodilation.
Most research so far has focused on flow‐mediated dilation (FMD) only; the effects on other …

Effects of high flavanol dark chocolate on cardiovascular function and platelet aggregation

G Rull, ZN Mohd-Zain, J Shiel, MH Lundberg… - Vascular …, 2015 - Elsevier
Regular consumption of chocolate and cocoa products has been linked to reduced
cardiovascular mortality. This study compared the effects of high flavanol dark chocolate …

[HTML][HTML] Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons

D Grassi, C Lippi, S Necozione, G Desideri… - The American journal of …, 2005 - Elsevier
Background: Numerous studies indicate that flavanols may exert significant vascular
protection because of their antioxidant properties and increased nitric oxide bioavailability …

High‐polyphenol chocolate reduces endothelial dysfunction and oxidative stress during acute transient hyperglycaemia in Type 2 diabetes: a pilot randomized …

DD Mellor, LA Madden, KA Smith… - Diabetic …, 2013 - Wiley Online Library
Aims To investigate the effects of high‐polyphenol chocolate upon endothelial function and
oxidative stress in Type 2 diabetes mellitus during acute transient hyperglycaemia induced …