A review of malaria vaccine clinical projects based on the WHO rainbow table

L Schwartz, GV Brown, B Genton, VS Moorthy - Malaria journal, 2012 - Springer
Abstract Development and Phase 3 testing of the most advanced malaria vaccine, RTS,
S/AS01, indicates that malaria vaccine R&D is moving into a new phase. Field trials of …

Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium

CH Coelho, JYA Doritchamou, I Zaidi, PE Duffy - npj Vaccines, 2017 - nature.com
Abstract The Malaria Vaccine Symposium occurred at Johns Hopkins University in
Baltimore, MD, USA on April 25th, 2017, coinciding with World Malaria Day and the WHO …

The march toward malaria vaccines

SL Hoffman, J Vekemans, TL Richie, PE Duffy - Vaccine, 2015 - Elsevier
In 2013 there were an estimated 584,000 deaths and 198 million clinical illnesses due to
malaria, the majority in sub-Saharan Africa. Vaccines would be the ideal addition to the …

Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects

AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half
of the world population is still exposed to the risk of contracting malaria. Developing an …

[HTML][HTML] Update on the clinical development of candidate malaria vaccines

WR Ballou, M Arevalo-Herrera, D Carucci… - … Intolerable Burden of …, 2004 - ncbi.nlm.nih.gov
The recent availability of significantly increased levels of funding for unmet medical needs in
the developing world, made available by newly created public-private-partnerships, has …

[HTML][HTML] Status of vaccine research and development of vaccines for malaria

AJ Birkett - Vaccine, 2016 - Elsevier
Despite recent progress in reducing deaths attributable to malaria, it continues to claim
approximately 500,000 lives per year and is associated with approximately 200 million …

Efficacy of phase 3 trial of RTS, S/AS01 malaria vaccine: the need for an alternative development plan

S Mahmoudi, H Keshavarz - Human vaccines & …, 2017 - Taylor & Francis
Although vaccines would be the ideal tool for control, prevention, elimination, and
eradication of many infectious diseases, developing of parasites vaccines such as malaria …

Vaccines for malaria: how close are we?

MA Thera, CV Plowe - Annual review of medicine, 2012 - annualreviews.org
Vaccines are the most powerful public health tools mankind has created, but malaria
parasites are bigger, more complicated, and wilier than the viruses and bacteria that have …

Escaping the immune system: How the malaria parasite makes vaccine development a challenge

DI Stanisic, AE Barry, MF Good - Trends in parasitology, 2013 - cell.com
Malaria is a major cause of morbidity and mortality. Immunity is acquired but is suboptimal,
being slow to develop and incomplete. An inadequate understanding of natural immunity …

Plasmodium falciparum malaria vaccines in development

J Vekemans, WR Ballou - Expert review of vaccines, 2008 - Taylor & Francis
The development and implementation of a malaria vaccine would constitute a major
breakthrough for global health. Recently, numerous new candidates have entered clinical …