SphK1/S1P signaling pathway is involved in the development of hepatic inflammation and
injury. But its role in high fructose-induced NAFLD has not yet been reported. The aim of this …

Morin is a natural bioflavonoid that exhibits antioxidant and anti-inflammatory properties.
The present study was designed to evaluate the effect of morin on insulin resistance …

Renin-angiotensin-aldosterone system (RAS) has been implicated in non-alcoholic fatty
liver disease (NAFLD); the most common cause of chronic liver diseases. There is …

Non‐alcohol fatty liver disease (NAFLD) is a common disease which causes serious liver
damage. Geniposide (GEN), a kind of iridoid glycoside extracted from Gardenia jasminoides …

Morin (MO), a natural bioflavinoid, exists in many herbs. Previous studies have acclaimed
MO's anti‐inflammatory, antidiabetic, antioxidant, antifibrotic, anticancer, and …

Background Worldwide growing rates of obesity are correlated with the rising prevalence of
nonalcoholic fatty liver disease (NAFLD) with limited available therapeutics. Aim The present …

The dried fruit of Sophora japonica L. is a traditional Chinese herb tea rich in sophoricoside
that is an isoflavone glycoside. The aim of current study was to investigate the hepatic …

Nonalcoholic fatty liver disease (NAFLD) has become one of the public health problems
globally. The occurrence of NAFLD is usually accompanied by a series of chronic metabolic …

Nonalcoholic fatty liver disease (NAFLD) is a major health concern. Endoplasmic reticulum
(ER) stress, inflammation, and metabolic dysfunctions may be targeted to prevent the …

Inflammation constitutes an important component of non-alcoholic fatty liver disease. STAT3
is a direct target of inflammatory cytokines, but also mediates glycolipid metabolism in the …