3D image registration is critical to ensure accurate detection of longitudinal changes in trabecular bone density, microstructure, and stiffness measurements in rat …

S Lan, S Luo, BK Huh, A Chandra, AR Altman, L Qin… - Bone, 2013 - Elsevier
In the recent decade, in vivo μCT scanners have become available to monitor temporal
changes in rodent bone in response to diseases and treatments. We investigated short-term …

Reproducibility of bone micro-architecture measurements in rodents by in vivo micro-computed tomography is maximized with three-dimensional image registration

KK Nishiyama, GM Campbell, RJ Klinck, SK Boyd - Bone, 2010 - Elsevier
In vivo micro-computed tomography (μCT) is a new method to monitor longitudinal changes
of bone micro-architecture. Common animal models of bone diseases are mice and rats …

Evaluation of in-vivo measurement errors associated with micro-computed tomography scans by means of the bone surface distance approach

Y Lu, M Boudiffa, E Dall'Ara, I Bellantuono… - Medical engineering & …, 2015 - Elsevier
In vivo micro-computed tomography (µCT) scanning is an important tool for longitudinal
monitoring of the bone adaptation process in animal models. However, the errors associated …

Three-dimensional image registration improves the long-term precision of in vivo micro-computed tomographic measurements in anabolic and catabolic mouse …

GM Campbell, S Tiwari, F Grundmann, N Purcz… - Calcified tissue …, 2014 - Springer
Micro-computed tomography (micro-CT) is a widely used technique to track bone structural
and mineral changes in small animals in vivo. Precise definition of volumes of interest (VOIs) …

[HTML][HTML] Development of a protocol to quantify local bone adaptation over space and time: Quantification of reproducibility

Y Lu, M Boudiffa, E Dall'Ara, I Bellantuono… - Journal of …, 2016 - Elsevier
In vivo micro-computed tomography (µCT) scanning of small rodents is a powerful method
for longitudinal monitoring of bone adaptation. However, the life-time bone growth in small …

Noninvasive in vivo monitoring of bone architecture alterations in hindlimb‐unloaded female rats using novel three‐dimensional microcomputed tomography

V David, N Laroche, B Boudignon… - Journal of Bone and …, 2003 - academic.oup.com
We tested a novel microcomputed tomograph designed to longitudinally and noninvasively
monitor bone alterations in hindlimb‐unloaded female rats at a resolution of 26 μm over a …

Detecting and tracking local changes in the tibiae of individual rats: a novel method to analyse longitudinal in vivo micro-CT data

JH Waarsing, JS Day, JC Van Der Linden… - Bone, 2004 - Elsevier
In this study we present the analysis of in vivo micro-CT scans using a new method based
on image registration that accurately evaluates longitudinal micro-CT studies. We tested if …

Comparison of ex vivo and in vivo micro‐computed tomography of rat tibia at different scanning settings

AB Longo, PL Salmon, WE Ward - Journal of Orthopaedic …, 2017 - Wiley Online Library
The parameters of a micro‐computed tomography (μCT) scan, including whether a bone is
imaged in vivo or ex vivo, determine the quality of the resulting image. In turn, this impacts …

Mineralization kinetics in murine trabecular bone quantified by time-lapsed in vivo micro-computed tomography

C Lukas, D Ruffoni, FM Lambers, FA Schulte, G Kuhn… - Bone, 2013 - Elsevier
Trabecular bone is a highly dynamic tissue due to bone remodeling, mineralization and
demineralization. The mineral content and its spatial heterogeneity are main contributors to …

Evaluation of Three-dimensional Image Registration Methodologies for In Vivo Micro-computed Tomography

SK Boyd, S Moser, M Kuhn, RJ Klinck… - Annals of biomedical …, 2006 - Springer
The advent of in vivo micro-computed tomography (micro-CT) provides a novel approach to
measure the temporal adaptation of bone micro-architecture within an individual. Spatial …