Over the past 60 years, a great wealth of information on the natural history of the disease
has been collected. Despite this, MS prognosis keeps puzzling clinicians and remains …

Multiple sclerosis (MS) is a chronic neurologic disease with onset occurring predominantly
in young adults. As such, the disease evolves throughout several decades and the affected …

Establishing the prognosis for multiple sclerosis (MS) early in the disease course is critically
important for patients who develop this disease. Potentially, this information could be used to …

Natural history of multiple sclerosis: risk factors and prog... : Current Opinion in Neurology
Natural history of multiple sclerosis: risk factors and prognostic indicators : Current Opinion in …

Sir, The relationship between cumulative relapses and unremitting progressive disability is
highly relevant to clinical practice and to randomized controlled trial design …

Abstract Knowledge of the epidemiology and natural history of multiple sclerosis (MS) is
essential for practitioners and patients to make informed decisions about their care. This …

The level of future impairment is difficult to predict with multiple sclerosis (MS). Previous MS
prognosis studies have mainly examined mortality or overall impairment and have used …

A number of recent advances have been made in the clinical diagnosis and prognostication
of multiple sclerosis patients. Future research will enable the development of more accurate …

Globally, the course and prognosis of multiple sclerosis are heterogeneous, and generally
considered to be unpredictable. Advances in statistical techniques have made it possible to …

I. INTRODUCTION The natural history of multiple sclerosis has been the topic of numerous
studies for decades. The analysis of large and disease-representative cohorts of patients …