Elevated blood pressure has an impact on the vasculature as a consequence of both the
mechanical effects of blood pressure and shear stress, as well as the action of hormonal …

Vascular remodeling is characterized by the structural modifications of large and small
arteries causing alteration of lumen size and change in diameter. Essential hypertension is …

Hypertension is associated with alterations in the structure, function, and mechanical
properties of large and small arteries. Changes in the endothelium, smooth muscle cell …

Essential hypertension is characterized by an increase in total peripheral vascular
resistance, due primarily to a decrease in lumen diameter and an increase in media …

The different vascular phenotypes found in hypertension comprise different aspects. They
may be clinical, diagnostic, structural, mechanical, functional, cellular and extracellular …

Large conduit arteries and the microcirculation participate in the mechanisms of elevation of
blood pressure (BP). Large vessels play roles predominantly in older subjects, with stiffening …

In hypertension, the thickening of the arterial wall by an increase in the cellular mass and
collagen and elastin content may be considered to be an adaptive response to the high …

Hypertension is a highly prevalent multifactorial disease, affecting approximately 1 billion
adults worldwide. It is observed in≈ 30% of adults and an additional 30% of adults are at …

The basic hemodynamic abnormality in hypertension is an increased peripheral resistance
that is due mainly to a decreased vascular lumen derived from structural changes in the …

Hypertension-related end-organ damage results from blood pressure load and
neurohormonal activation and it is mainly a consequence of the vascular injury that takes …