The high prevalence of vitamin D deficiency in patients with chronic kidney disease is
believed to be an important risk factor for the cardiorenal syndrome commonly seen in this …

Although the endocrine effects of vitamin D are widely recognized, somewhat less
appreciated is that vitamin D may serve paracrine functions through local activation by 1-α …

The effects of vitamin D receptor activation on cardiovascular diseases, especially
hypertension and cardiac dysfunction, are areas of active investigation. This article reviews …

Vitamin D3 needs to be activated into 1, 25-dihydroxyvitamin D3 in order to bind to vitamin D
receptor (VDR) for functional responses. Studies in the past have focussed on the role of …

For a long time, vitamin D was regarded as an essential component for the maintenance of
appropriate calcium metabolism. Indeed, the calcium-related functions were broadly studied …

Vitamin D has been recently associated with several renal, cardiovascular and inflammatory
diseases, beyond mineral metabolism and bone health. This is due in part to widespread …

Vitamin D and its analogs have antiproteinuric activity and podocytes express the vitamin D
receptor, but whether vitamin D signaling in podocytes accounts for this renoprotection is …

Diabetic nephropathy (DN), one of the most common and severe microvascular
complications of diabetes mellitus (DM), is an important risk factor for DM patient's death …

While it is true that many traditional cardiovascular risk factors are amenable to intervention
in chronic kidney disease (CKD), the results of intervention may not be as efficacious as …

Chronic kidney disease (CKD) independently increases the rates of cardiovascular disease,
whereas the severity of kidney disease correlates with increased cardiovascular morbidity …