Arterial and Venous Endothelia Display Differential Functional Fractalkine (CX3CL1) Expression by Angiotensin-II
C Rius, L Piqueras, H González-Navarro… - … and Vascular Biology, 2013 - Am Heart Assoc
Objective—Angiotensin-II (Ang-II) promotes the interaction of mononuclear cells with
arterioles and neutrophils with postcapillary venules. To investigate the mechanisms …
arterioles and neutrophils with postcapillary venules. To investigate the mechanisms …
Characterization of Synergistic Induction of CX3CL1/Fractalkine by TNF-α and IFN-γ in vascular endothelial cells: an essential role for TNF-α in post-transcriptional …
T Matsumiya, K Ota, T Imaizumi, H Yoshida… - The Journal of …, 2010 - journals.aai.org
Abstract CX3CL1/Fractalkine, a chemokine specific to monocytes and NK cells, is induced
synergistically by TNF-α and IFN-γ in vascular endothelial cells. However, the mechanism …
synergistically by TNF-α and IFN-γ in vascular endothelial cells. However, the mechanism …
Regulation of CX3CL1/fractalkine expression in endothelial cells
T Imaizumi, H Yoshida, K Satoh - Journal of atherosclerosis and …, 2004 - jstage.jst.go.jp
CX3CL1/fractalkine is a chemokine with a unique CX3C motif. Fractalkine is synthesized in
endothelial cells as a membrane protein, and the N-terminal domain containing a CX3C …
endothelial cells as a membrane protein, and the N-terminal domain containing a CX3C …
Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated …
C Schulz, A Schäfer, M Stolla, S Kerstan, M Lorenz… - Circulation, 2007 - Am Heart Assoc
Background—The membrane-bound chemokine fractalkine (CX3CL1) is expressed on
various cell types such as activated endothelial cells and has been implicated in the …
various cell types such as activated endothelial cells and has been implicated in the …
Fractalkine promotes human monocyte survival via a reduction in oxidative stress
GE White, E McNeill, KM Channon… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—The CX3C chemokine fractalkine (CX3CL1) has a critical role in the
development of atherogenesis because apolipoprotein-E–deficient mice lacking CX3CL1 or …
development of atherogenesis because apolipoprotein-E–deficient mice lacking CX3CL1 or …
Fractalkine/CX3CL1 production by human aortic smooth muscle cells impairs monocyte procoagulant and inflammatory responses
V Ollivier, S Faure, N Tarantino, S Chollet-Martin… - Cytokine, 2003 - Elsevier
Expression of membrane-bound CX3CL1, a CX3C chemokine, can be strongly induced by
inflammatory cytokines in primary endothelial cells, mediating capture and tight adhesion of …
inflammatory cytokines in primary endothelial cells, mediating capture and tight adhesion of …
Fractalkine in vascular biology: from basic research to clinical disease
H Umehara, ET Bloom, T Okazaki… - … , and vascular biology, 2004 - Am Heart Assoc
Fractalkine (now also called CX3CL1) is a unique chemokine that functions not only as a
chemoattractant but also as an adhesion molecule and is expressed on endothelial cells …
chemoattractant but also as an adhesion molecule and is expressed on endothelial cells …
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy
JK Damås, A Boullier, T Wæhre, C Smith… - … , and vascular biology, 2005 - Am Heart Assoc
Objective—Recent data derived primarily from studies in animal models suggest that
fractalkine (CX3CL1) and its cognate receptor, CX3CR1, play a role in atherogenesis. We …
fractalkine (CX3CL1) and its cognate receptor, CX3CR1, play a role in atherogenesis. We …
Fractalkine (CX3CL1) stimulated by nuclear factor kappaB (NF-kappaB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an …
B Chandrasekar, S Mummidi, RP Perla… - Biochemical …, 2003 - portlandpress.com
Fractalkine (also known as CX3CL1), a CX3C chemokine, activates and attracts monocytes/
macrophages to the site of injury/inflammation. It binds to CX3C receptor 1 (CX3CR1), a …
macrophages to the site of injury/inflammation. It binds to CX3C receptor 1 (CX3CR1), a …
Activation of fractalkine/CX3CR1 by vascular endothelial cells induces angiogenesis through VEGF-A/KDR and reverses hindlimb ischaemia
J Ryu, CW Lee, KH Hong, JA Shin, SH Lim… - Cardiovascular …, 2008 - academic.oup.com
Aims The present study investigated the detailed mechanism by which fractalkine (Fkn), a
CX3C chemokine, induces angiogenesis and its functional implication in alleviating …
CX3C chemokine, induces angiogenesis and its functional implication in alleviating …