Diseño, síntesis y evaluación biológica de nuevos derivados de 1, 4-di-N-óxido de quinoxalina como potenciales agentes antichagásicos

E Torres - 2013 - dadun.unav.edu
El principal objetivo de este trabajo es el diseño y síntesis de nuevos derivados de
quinoxalina 1, 4-di-N-óxido que curen la enfermedad de Chagas. La estrategia seguida …

Diseño, síntesis y evaluación biológica de nuevos derivados de quinoxalina y 1, 4-di-n-óxido de quinoxalina con aplicación en diferentes áreas terapéuticas

MAB Pérez - 2010 - dialnet.unirioja.es
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW QUINOXALINE AND
QUINOXALINE 1, 4-di-N-OXIDE DERIVATIVES WITH APPLICATION IN DIFFERENT …

[PDF][PDF] Quinoxaline 1, 4-di-N-oxide derivatives: interest in the treatment of chagas disease

E Moreno-Viguri, S Pérez-Silanes - Rev. Virtual Quím, 2013 - academia.edu
More than 100 million people are at risk of contracting Chagas disease. It is estimated that in
2008, Chagas disease was responsible for the death of more than 10,000 people. Despite …

2D-QSAR ANALYSIS OF DERIVATIVES OF QUINOXALINE 1,4-DI-N-OXIDES WITH ACTIVITY AGAINST CHAGAS' DISEASE

CJ Guerra, JM López, SF Figueredo, AE Muñoz… - Química …, 2016 - SciELO Brasil
SciELO-Brasil-ANALISIS QSAR-2D DE LOS DERIVADOS DE 1, 4-DI-< i> N-</i> OXIDOS DE
QUINOXALINA CON ACTIVIDAD CONTRA LA ENFERMEDAD DE CHAGAS ANALISIS …

Current status of quinoxaline and quinoxaline 1,4‐di‐N‐oxides derivatives as potential antiparasitic agents

J Soto‐Sánchez, JD Ospina‐Villa - Chemical Biology & Drug …, 2021 - Wiley Online Library
Parasitic diseases are a public health problem, especially in developing countries where
millions of people are affected every year. Current treatments have several drawbacks …

Derivados de 1, 4-di-N-óxido de quinoxalina y enfermedades olvidadas

E Vicente, B Solano, A Burguete, S Ancizu… - 2007 - dadun.unav.edu
Las enfermedades olvidadas son un grupo de enfermedades infecciosas médicamente
diversas entre las que se encuentran tuberculosis, malaria, leishmaniasis y la enfermedad …

Novel quinoxaline 1, 4-di-N-oxide derivatives as new potential antichagasic agents

E Torres, E Moreno-Viguri, S Galiano… - European journal of …, 2013 - Elsevier
As a continuation of our research and with the aim of obtaining new agents against Chagas
disease, an extremely neglected disease which threatens 100 million people, eighteen new …

Quinoxalinas como potenciales agentes Antimycobacterium tuberculosis: una revisión

M Santivañez-Veliz, E Moreno-Viguri… - Revista de la …, 2013 - scielo.org.pe
La tuberculosis requiere nuevos tratamientos frente a su compleja resistencia como MDR-
TB y XDR-TB. Las quinoxalinas presentan una amplia variedad de propiedades biológicas …

Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity

S Pérez-Silanes, E Torres, L Arbillaga, J Varela… - Bioorganic & medicinal …, 2016 - Elsevier
We report the synthesis and in vitro activity against Trypanosoma cruzi epimastigotes of 15
novel quinoxaline derivatives. Ten of the derivatives presented IC 50 values lower than the …

New Quinoxalines with Biological Applications

M Vieira, R Ferraz, R Fernandes… - Biochemistry and …, 2014 - recipp.ipp.pt
In search of alternatives to antimicrobial agents currently in use, and in order to respond to
the landscape of loss of efficacy due to the emergence of resistance, several research …