[HTML][HTML] New Arabidopsis thaliana cytochrome c partners: a look into the elusive role of cytochrome c in programmed cell death in plants

J Martínez-Fábregas, I Díaz-Moreno… - Molecular & Cellular …, 2013 - ASBMB
Programmed cell death is an event displayed by many different organisms along the
evolutionary scale. In plants, programmed cell death is necessary for development and the …

[HTML][HTML] Structural and functional analysis of novel human cytochrome c targets in apoptosis

J Martínez-Fábregas, I Díaz-Moreno… - Molecular & Cellular …, 2014 - ASBMB
Since the first description of apoptosis four decades ago, great efforts have been made to
elucidate, both in vivo and in vitro, the molecular mechanisms involved in its regulation …

Proposed mechanism for regulation of H2O2‐induced programmed cell death in plants by binding of cytochrome c to 14‐3‐3 proteins

CA Elena‐Real, K González‐Arzola… - The Plant …, 2021 - Wiley Online Library
Programmed cell death (PCD) is crucial for development and homeostasis of all multicellular
organisms. In human cells, the double role of extra‐mitochondrial cytochrome c in triggering …

[HTML][HTML] Post-Translational Modifications of Cytochrome c in Cell Life and Disease

A Guerra-Castellano, I Márquez… - International journal of …, 2020 - mdpi.com
Mitochondria are the powerhouses of the cell, whilst their malfunction is related to several
human pathologies, including neurodegenerative diseases, cardiovascular diseases, and …

Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death?

JT Hancock, R Desikan, SJ Neill - Free Radical Biology and Medicine, 2001 - Elsevier
It has now become recognized that one of the key events in the induction of apoptosis, or
programmed cell death, in both plants and animals is the release of cytochrome c from …

Cytochrome c, a hub linking energy, redox, stress and signaling pathways in mitochondria and other cell compartments

E Welchen, DH Gonzalez - Physiologia plantarum, 2016 - Wiley Online Library
Cytochrome c (CYT c) is a soluble redox‐active heme protein that transfers electrons from
complex III to complex IV in the cyanide‐sensitive mitochondrial respiratory pathway. CYT c …

Cytochrome c: An extreme multifunctional protein with a key role in cell fate

R Santucci, F Sinibaldi, P Cozza, F Polticelli… - International journal of …, 2019 - Elsevier
Cytochrome c, a protein that belongs to class 1 of the c-type cytochrome family, exerts
different functions depending on its cellular localization and the conditions in which it …

A proteomic analysis of plant programmed cell death

JA Swidzinski, CJ Leaver, LJ Sweetlove - Phytochemistry, 2004 - Elsevier
Programmed cell death (PCD) is an active cellular suicide that occurs in animals and plants
throughout development and in response to both abiotic and biotic stresses. In contrast to …

The role of key residues in structure, function, and stability of cytochrome-c

S Zaidi, MI Hassan, A Islam, F Ahmad - Cellular and molecular life …, 2014 - Springer
Abstract Cytochrome-c (cyt-c), a multi-functional protein, plays a significant role in the
electron transport chain, and thus is indispensable in the energy-production process …

[HTML][HTML] Cytochrome c: using biological insight toward engineering an optimized anticancer biodrug

LJ Delinois, O De Leon-Velez, A Vázquez-Medina… - Inorganics, 2021 - mdpi.com
The heme protein cytochrome c (Cyt c) plays pivotal roles in cellular life and death
processes. In the respiratory chain of mitochondria, it serves as an electron transfer protein …