The discovery of stem and progenitor cells in the adult mammalian heart has added a vital
dimension to the field of cardiac regeneration. Cardiac-resident stem cells are likely …

Thymosin beta4 (TB4) has multiple functions in cellular response in processes as diverse as
embryonic organ development and the pathogeneses of disease, especially those …

Putative cardiac progenitor cells (CPCs) have been identified in the myocardium and are
regarded as promising candidates for cardiac cell-based therapies. Although two distinct …

ABSTRACT Thymosin β4 (Tβ4) is a regenerative peptide that we hypothesized would
promote healing of fractured bone. Mice received a bilateral fibular osteotomy and were …

Considering the impaired regenerative capacity of adult mammalian heart tissue,
cardiovascular tissue engineering aims to create functional substitutes that can restore the …

Understanding heart development is of fundamental importance, because the heart organ is
the first functional organ in mammalian embryos and heart function is unremittingly required …

The parameters of culturing and purification of thymosin-beta 4 were optimized, and the
stages of culturing and laboratory method for its isolation were scaled up to the pilot process …

Previous studies have shown that the recombination of cells liberated from developing tooth
germs develop into teeth. However, it is difficult to use human developing tooth germ as a …

Abstract Bone morphogenetic protein 1 (BMP1) was originally isolated from bone with other
BMPs due to its affinity for heparin. While all other BMPs are members of the Transforming …

Regenerative medicine for skeletal and cardiac muscles still constitutes a fascinating and
ambitious frontier. In this perspective, understanding the possibilities of intrinsic cell …