PPAR-γ agonist GW1929 but not antagonist GW9662 reduces TBBPA-induced neurotoxicity in primary neocortical cells

AK Wojtowicz, KA Szychowski, M Kajta - Neurotoxicity Research, 2014 - Springer
Abstract Tetrabromobisphenol A (2, 2-bis (4-hydroxy-3, 5-dibromophenyl) propane; TBBPA)
is a widely used brominated flame retardant. TBBPA induces neuronal damage, but the …

Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice

A Nakajima, D Saigusa, N Tetsu, T Yamakuni… - Toxicology letters, 2009 - Elsevier
Tetrabromobisphenol A (TBBPA) is widely used as a flame retardant and is suspected to be
stable in the environment with possible widespread human exposures. In the present study …

TBBPA causes neurotoxic and the apoptotic responses in cultured mouse hippocampal neurons in vitro

KA Szychowski, AK Wójtowicz - Pharmacological Reports, 2016 - Springer
Abstract Background Tetrabromobisphenol A (TBBPA) is a brominated flame retardant
widely used in a variety of commercial and household products. TBBPA can become …

In Vitro Toxicity of Tetrabromobisphenol-A on Cerebellar Granule Cells: Cell Death, Free Radical Formation, Calcium Influx and Extracellular Glutamate

T Reistad, E Mariussen, A Ring… - Toxicological …, 2007 - academic.oup.com
Tetrabromobisphenol-A (TBBPA) is one of the worlds most widely used brominated flame
retardant. The present study reports effects of TBBPA on primary cultures of cerebellar …

Synergistic neurotoxicity of oxygen-glucose deprivation and tetrabromobisphenol A in vitro: role of oxidative stress

E Ziemińska, A Stafiej, B Toczyłowska… - Pharmacological …, 2012 - Springer
Background Tetrabromobisphenol A (TBBPA) is a toxic brominated flame retardant.
Previous studies have demonstrated that exposure of primary cultures of rat cerebellar …

Multiple Novel Modes of Action Involved in the In Vitro Neurotoxic Effects of Tetrabromobisphenol-A

HS Hendriks, RGDM van Kleef… - Toxicological …, 2012 - academic.oup.com
Neurotoxicological data on the widely used brominated flame retardant tetrabromobisphenol-
A (TBBPA) is limited. Since recent studies indicated that inhibitory GABAA and excitatory …

Tetrabromobisphenol A-induced apoptosis in neural stem cells through oxidative stress and mitochondrial dysfunction

JH Cho, S Lee, H Jeon, AH Kim, W Lee, Y Lee… - Neurotoxicity …, 2020 - Springer
Tetrabromobisphenol A (TBBPA) is widely used in materials like plastics and textiles as a
fire retardant. In a previous study, we reported TBBPA might disrupt hippocampal …

High dose tetrabromobisphenol A impairs hippocampal neurogenesis and memory retention

AH Kim, HJ Chun, S Lee, HS Kim, J Lee - Food and Chemical Toxicology, 2017 - Elsevier
Tetrabromobisphenol A (TBBPA) is a brominated flame retardant that is commonly used in
commercial and household products, such as, computers, televisions, mobile phones, and …

Absence of neurotoxicity and lack of neurobehavioral consequences due to exposure to tetrabromobisphenol A (TBBPA) exposure in humans, animals and zebrafish

S Kacew, AW Hayes - Archives of toxicology, 2020 - Springer
Abstract Tetrabromobisphenol A (2, 2′, 6, 6′-tetrabromo-4, 4′-isopropylidenediphenol,
CAS no. 79-94-7)(TBBPA) is an effective brominated flame retardant present in many …

Differences in neonatal neurotoxicity of brominated flame retardants, PBDE 99 and TBBPA, in mice

H Viberg, P Eriksson - Toxicology, 2011 - Elsevier
Flame retardants such as polybrominated diphenyl ethers (PBDE) and tetrabromobisphenol
A are used as flame retardants and detected in the environmental, wildlife species and …