Therapeutic approaches to chronic hyperuricemia and gout

D Grassi, R Pontremoli, R Bocale, C Ferri… - High Blood Pressure & …, 2014 - Springer
Gout is currently one of the most common causes of inflammatory arthritis in most
industrialised countries. Apart from its high frequency, gout is associated with disability, poor …

Gout: overview and newer therapeutic developments.

ML Hilaire, JR Wozniak - Formulary, 2010 - search.ebscohost.com
Gout is a chronic, progressive disease that is increasing in prevalence, it results from the
deposition of urate crystals caused by the overproduction or underexcretion of uric acid. The …

Overview of serum uric acid treatment targets in gout: why less than 6 mg/dL?

G Ruoff, NL Edwards - Postgraduate medicine, 2016 - Taylor & Francis
Gout is a progressive, painful, debilitating form of inflammatory arthritis. It is caused by
factors that elevate the concentration of serum uric acid (sUA), leading to hyperuricemia …

Gout: optimizing treatment to achieve a disease cure

JA Bernal, N Quilis, M Andrés… - … advances in chronic …, 2016 - journals.sagepub.com
Gout is one of the most common inflammatory arthritides. The disease is due to the
deposition of monosodium urate crystals. These deposits are reversible with proper …

An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia

M Bove, AFG Cicero, M Veronesi… - Vascular Health and Risk …, 2017 - Taylor & Francis
Several studies suggest that chronic hyperuricemia, the main precursor of gout, is involved
in the pathogenesis of different systemic disorders that affect cardiovascular and renal …

Evaluation and treatment of gout as a chronic disease

F Perez-Ruiz, AM Herrero-Beites - Advances in therapy, 2012 - Springer
Gout is a disease caused by deposition of monosodium urate crystals in tissues. One of the
limitations for successful treatment of gout is to consider it as an intermittent disease rather …

[PDF][PDF] Hyperuricaemia and gout

M Shipley - JR Coll Physicians Edinb, 2011 - rcpe.ac.uk
Gout is increasing in prevalence throughout the world, particularly in developed countries.
The causes are dietary–purine-rich foods, high saturated fats, fructose-containing drinks and …

Optimizing current treatment of gout

F Rees, M Hui, M Doherty - Nature Reviews Rheumatology, 2014 - nature.com
Gout is the most common inflammatory arthritis worldwide. Although effective treatments
exist to eliminate sodium urate crystals and to'cure'the disease, the management of gout is …

[HTML][HTML] Gout—current diagnosis and treatment

AK Tausche, TL Jansen, HE Schröder… - Deutsches Ärzteblatt …, 2009 - ncbi.nlm.nih.gov
Background Because of the changing dietary habits of an aging population, hyperuricemia
is frequently found in combination with other metabolic disorders. Longstanding elevation of …

Reducing uric acid as a means to prevent cardiovascular and renal disease

S Watanabe, J Kanellis, T Nakagawa… - Expert Opinion on …, 2002 - Taylor & Francis
Hyperuricaemia (uric acid levels> 6.5 mg/dl in men and> 6.0 mg/dl in women) affects~ 10%
of the population but is not classically treated with uric acid-lowering drugs unless there is a …