Psychological stress contributes to the onset and exacerbation of nearly all neuropsychiatric
disorders. Individual differences in stress-regulatory circuits can therefore dramatically affect …

When facing stress, most individuals are resilient whereas others are prone to developing
mood disorders. The brain mechanisms underlying such divergent behavioral responses …

Exposure to unpredictable environmental stress is widely recognized as a major
determinant for risk and severity in neuropsychiatric disorders such as major depressive …

Chronic psychosocial stress is a well-established risk factor for neuropsychiatric diseases.
Abnormalities in brain activity have been demonstrated in patients with stress-related …

Stressful life events are ubiquitous and well-known to negatively impact mental health.
However, in both humans and animal models, there is large individual variability in how …

The prefrontal cortex (PFC)—the most evolved brain region—subserves our highest-order
cognitive abilities. However, it is also the brain region that is most sensitive to the detrimental …

Chronic stress‐related psychiatric diseases, such as major depression, posttraumatic stress
disorder, and schizophrenia, are characterized by a maladaptive organization of behavioral …

A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of
the newly evolved prefrontal cortex (PFC). Exposure to acute, uncontrollable stress …

In response to extreme stress, individuals either show resilience or succumb to despair. The
prefrontal cortex (PFC) is required for coping with stress, and PFC dysfunction has been …

Circuits distributed across cortico-limbic brain regions compose the networks that mediate
emotional behavior. The prefrontal cortex (PFC) regulates ultraslow (< 1 Hz) dynamics …