The synthesis and antiprotozoal activity of some 3-alkoxy-1-alkyl-(1, 4) and 3-alkoxy-1-(ω-
aminoalkyl)-5-nitroindazoles (2, 3, 5–8) against different morphological forms of …

Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and
benznidazole, is far from satisfactory and therefore the development of new antichagasic …

Two series of new 5-nitroindazole derivatives, 1-substituted 2-benzylindazolin-3-ones (6–
29, series A) and 3-alkoxy-2-benzyl-2H-indazoles (30–37, series B), containing differently …

Twelve molecules from a series of 35 new 5-nitroindazole derivatives, selected from a
successful primary screening on Trypanosoma cruzi epimastigotes, have been evaluated …

In this study, a new series of eleven 5-nitroindazole derivatives (10− 20) and a related 6-
nitroquinazoline (21) was synthesized and tested in vitro against different forms of the …

We have previously shown that 3-nitro-1H-1, 2, 4-triazole-based arylamides and
arylsulfonamides demonstrate significant activity in vitro against Trypanosoma cruzi, the …

New 5-nitroindazole derivatives were developed and their antichagasic properties studied.
Eight compounds (14–18, 20, 26 and 28) displayed remarkable in vitro activities against …

The antiparasitic activity of azole and new 4-aminopyridine derivatives has been
investigated. The imidazoles 1 and 3–5 showed a potent in vitro antichagasic activity with …

Three different series of new 5‐nitroindazole derivatives—1‐(ω‐aminoalkyl)‐2‐
benzylindazolin‐3‐ones (series A; ten compounds), 3‐(ω‐aminoalkoxy)‐2‐benzylindazoles …

Nitrotriazole-based compounds belonging to various chemical subclasses were found to be
very effective against Chagas disease both in vitro and in vivo after a short administration …