[HTML][HTML] Interference with PPARγ in Vascular Smooth Muscle Causes Baroreflex Impairment and Autonomic Dysfunction

GR Borges, DA Morgan, P Ketsawatsomkron… - …, 2014 - ncbi.nlm.nih.gov
Abstract S-P467L mice expressing dominant negative Peroxisome Proliferator Activated
Receptor-γ selectively in vascular smooth muscle, exhibit impaired vasodilation, augmented …

Interference with peroxisome proliferator-activated receptor-γ in vascular smooth muscle causes baroreflex impairment and autonomic dysfunction

GR Borges, DA Morgan, P Ketsawatsomkron… - …, 2014 - Am Heart Assoc
S-P467L mice expressing dominant negative peroxisome proliferator-activated receptor-γ
selectively in vascular smooth muscle exhibit impaired vasodilation, augmented …

[PDF][PDF] Nervous System

GR Borges, DA Morgan, P Ketsawatsomkron… - 2014 - academia.edu
S-P467L mice expressing dominant negative peroxisome proliferator-activated receptor-γ
selectively in vascular smooth muscle exhibit impaired vasodilation, augmented …

Cardiac autonomic function in mice expressing dominant‐negative mutation of PPAR‐gamma (PPARG) in vascular smooth muscle

GR Borges, CD Sigmund - The FASEB Journal, 2009 - Wiley Online Library
Mice expressing dominant‐negative PPARG in vascular smooth muscle (S‐P467L)
exhibited vascular dysfunction, hypertension and tachycardia. We hypothesize that a high …

Diverse impairment of vasodilator pathways in brain following selective interference with PPAR‐gamma in vascular muscle

ML Modrick, S Chrissobolis, CM Halabi… - The FASEB …, 2009 - Wiley Online Library
Peroxisome proliferator‐activated receptor‐gamma (PPARg) may play an important
protective role in the vasculature. We examined the hypothesis that selective interference …

Interference with Peroxisome Proliferator Activated Receptor Gamma (PPARG) in smooth muscle causes aortic dysfunction via a Rho‐kinase‐dependent mechanism

CJ Pelham, P Ketsawatsomkron, S Groh… - The FASEB …, 2010 - Wiley Online Library
Transgenic mice expressing a vascular muscle‐specific dominant negative mutant of
PPARG (S‐P467L) develop hypertension and aortic dysfunction, supporting a protective role …

Role of Peroxisome Proliferator–Activated Receptor-γ in Vascular Muscle in the Cerebral Circulation

TM De Silva, ML Modrick, P Ketsawatsomkron… - …, 2014 - Am Heart Assoc
Although peroxisome proliferator–activated receptor-γ (PPARγ) is thought to play a
protective role in the vasculature, its cell-specific effect, particularly in resistance vessels, is …

Vascular dysfunction in transgenic mice expressing a PPARγ interfering mutation specifically in vascular muscle: role of aortic rho kinase

P Ketsawatsomkron, WJ de Lange… - The FASEB …, 2009 - Wiley Online Library
PPARγ is a ligand activated transcription factor expressed in vascular muscle and
endothelium. We previously reported that targeted expression of a dominant negative …

[图书][B] Interference with peroxisome proliferator activated receptor gamma function in smooth muscle causes vascular dysfunction and hypertension

CM Halabi - 2009 - search.proquest.com
Peroxisome proliferator-activated receptor-γ (PPARγ), a member of the nuclear receptor
superfamily of ligand activated transcription factors, plays a critical role in adipogenesis and …

Genetic Interference with Peroxisome Proliferator-Activated Receptor?(PPAR?) in Smooth Muscle Augments Cerebrovascular Effects of Angiotensin I

M De Silva, L Modrick, P Ketsawatsomkron… - 2013 - Am Heart Assoc
Angiotensin II (Ang II) plays a major role in vascular disease, including both large and small
vessel disease in brain. PPARγ is a ligand-activated nuclear receptor that exerts protective …