GR Borges, CD Sigmund - The FASEB Journal, 2009 - Wiley Online Library
Mice expressing dominant‐negative PPARG in vascular smooth muscle (S‐P467L) exhibited vascular dysfunction, hypertension and tachycardia. We hypothesize that a high …
Peroxisome proliferator‐activated receptor‐gamma (PPARg) may play an important protective role in the vasculature. We examined the hypothesis that selective interference …
Transgenic mice expressing a vascular muscle‐specific dominant negative mutant of PPARG (S‐P467L) develop hypertension and aortic dysfunction, supporting a protective role …
Although peroxisome proliferator–activated receptor-γ (PPARγ) is thought to play a protective role in the vasculature, its cell-specific effect, particularly in resistance vessels, is …
P Ketsawatsomkron, WJ de Lange… - The FASEB …, 2009 - Wiley Online Library
PPARγ is a ligand activated transcription factor expressed in vascular muscle and endothelium. We previously reported that targeted expression of a dominant negative …
Peroxisome proliferator-activated receptor-γ (PPARγ), a member of the nuclear receptor superfamily of ligand activated transcription factors, plays a critical role in adipogenesis and …
Angiotensin II (Ang II) plays a major role in vascular disease, including both large and small vessel disease in brain. PPARγ is a ligand-activated nuclear receptor that exerts protective …