NOD-like receptors: versatile cytosolic sentinels

V Motta, F Soares, T Sun… - Physiological reviews, 2015 - journals.physiology.org
Nucleotide binding oligomerization domain (NOD)-like receptors are cytoplasmic pattern-
recognition receptors that together with RIG-I-like receptor (retinoic acid-inducible gene 1) …

The Nod-like receptor (NLR) family: a tale of similarities and differences

M Proell, SJ Riedl, JH Fritz, AM Rojas… - PloS one, 2008 - journals.plos.org
Innate immunity represents an important system with a variety of vital processes at the core
of many diseases. In recent years, the central role of the Nod-like receptor (NLR) protein …

Unleashing the therapeutic potential of NOD-like receptors

K Geddes, JG Magalhaes, SE Girardin - Nature reviews Drug discovery, 2009 - nature.com
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are a family of
intracellular sensors that have key roles in innate immunity and inflammation. Whereas …

NOD-like receptors: role in innate immunity and inflammatory disease

G Chen, MH Shaw, YG Kim… - Annual Review of …, 2009 - annualreviews.org
The NOD-like receptors (NLRs) are a specialized group of intracellular receptors that
represent a key component of the host innate immune system. Since the discovery of the first …

[HTML][HTML] Intracellular NOD-like receptors in host defense and disease

TD Kanneganti, M Lamkanfi, G Núñez - Immunity, 2007 - cell.com
The innate immune system comprises several classes of pattern recognition receptors,
including Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors …

Intracellular NOD‐like receptors in innate immunity, infection and disease

L Franchi, JH Park, MH Shaw… - Cellular …, 2008 - Wiley Online Library
The innate immune system comprises several classes of pattern‐recognition receptors,
including Toll‐like receptors (TLRs) and nucleotide binding and oligomerization domain‐like …

The role of NOD-like receptors in innate immunity

CLC Almeida-da-Silva, LEB Savio… - Frontiers in …, 2023 - frontiersin.org
The innate immune system in vertebrates and invertebrates relies on conserved receptors
and ligands, and pathways that can rapidly initiate the host response against microbial …

NOD‐like receptors interfacing the immune and reproductive systems

H Van Gorp, A Kuchmiy, F Van Hauwermeiren… - The FEBS …, 2014 - Wiley Online Library
Nucleotide‐binding oligomerization domain receptors (NOD‐like receptors, NLR s) are
intracellular proteins that are chiefly known for their critical functions in inflammatory …

Functions of NOD-like receptors in human diseases

Y Zhong, A Kinio, M Saleh - Frontiers in immunology, 2013 - frontiersin.org
Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly
conserved cytosolic pattern recognition receptors that perform critical functions in surveying …

[HTML][HTML] NOD-like receptors and human diseases

P Rosenstiel, A Till, S Schreiber - Microbes and infection, 2007 - Elsevier
NOD-like receptors are cytosolic proteins that contain a central nucleotide-binding
oligomerization domain (NACHT), an N-terminal effector-binding domain and C-terminal …