Regulation of Mec1 kinase activity by the SWI/SNF chromatin remodeling complex

P Kapoor, Y Bao, J Xiao, J Luo, J Shen… - Genes & …, 2015 - genesdev.cshlp.org
ATP-dependent chromatin remodeling complexes alter chromatin structure through
interactions with chromatin substrates such as DNA, histones, and nucleosomes. However …

Hst3 is regulated by Mec1-dependent proteolysis and controls the S phase checkpoint and sister chromatid cohesion by deacetylating histone H3 at lysine 56

S Thaminy, B Newcomb, J Kim, T Gatbonton… - Journal of Biological …, 2007 - ASBMB
The SIR2 homologues HST3 and HST4 have been implicated in maintenance of genome
integrity in the yeast Saccharomyces cerevisiae. We find that Hst3 has NAD-dependent …

The c-myc Gene Is a Direct Target of Mammalian SWI/SNF–Related Complexes during Differentiation-Associated Cell Cycle Arrest

NG Nagl Jr, DR Zweitzig, B Thimmapaya, GR Beck Jr… - Cancer research, 2006 - AACR
The activity of mammalian SWI/SNF–related chromatin remodeling complexes is crucial for
differentiation, development, and tumor suppression. Cell cycle–regulating activities …

Regulation of Histone Deposition Proteins Asf1/Hir1 by Multiple DNA Damage Checkpoint Kinases in Saccharomyces cerevisiae

JA Sharp, G Rizki, PD Kaufman - Genetics, 2005 - academic.oup.com
Abstract CAF-1, Hir proteins, and Asf1 are histone H3/H4 binding proteins important for
chromatin-mediated transcriptional silencing. We explored genetic and physical interactions …

Members of the hSWI/SNF chromatin remodeling complex associate with and are phosphorylated by protein kinase B/Akt

KSJ Foster, WJ McCrary, JS Ross, CF Wright - Oncogene, 2006 - nature.com
In an adenosine triphosphate (ATP)-dependent process, the hSWI/SNF chromatin
remodeling complex functions to alter chromatin structure, thereby regulating transcription …

Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes

LA Boyer, MR Langer, KA Crowley, S Tan, JM Denu… - Molecular cell, 2002 - cell.com
The SANT domain is a novel motif found in a number of eukaryotic transcriptional regulatory
proteins that was identified based on its homology to the DNA binding domain of c-myb …

Direct interactions promote eviction of the Sir3 heterochromatin protein by the SWI/SNF chromatin remodeling enzyme

BJ Manning, CL Peterson - Proceedings of the National …, 2014 - National Acad Sciences
Heterochromatin is a specialized chromatin structure that is central to eukaryotic
transcriptional regulation and genome stability. Despite its globally repressive role …

Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell‐cycle control

NG Nagl Jr, X Wang, A Patsialou, M Van Scoy… - The EMBO …, 2007 - embopress.org
The mammalian SWI/SNF chromatin remodeling complex is becoming increasingly
recognized for its role in tumor suppression, based on its ability to regulate accessibility of …

A proteome-wide analysis of kinase-substrate network in the DNA damage response

S Chen, CP Albuquerque, J Liang… - Journal of Biological …, 2010 - ASBMB
The DNA damage checkpoint, consisting of an evolutionarily conserved protein kinase
cascade, controls the DNA damage response in eukaryotes. Knowledge of the in vivo …

Chromatin remodeling by the SWI/SNF complex is essential for transcription mediated by the yeast cell wall integrity MAPK pathway

AB Sanz, R García, JM Rodríguez-Peña… - Molecular biology of …, 2012 - Am Soc Cell Biol
In Saccharomyces cerevisiae, the transcriptional program triggered by cell wall stress is
coordinated by Slt2/Mpk1, the mitogen-activated protein kinase (MAPK) of the cell wall …