The objective of the INTEGRATE project (http://www. fp7-integrate. eu/) that has recently
concluded successfully was the development of innovative biomedical applications focused …

Objectives: To propose a modification to current methodologies for clinical trials, improving
data collection and cost-efficiency. To describe a system to integrate distributed and …

Background Breast cancer is one of the most common cancer types. Due to the complexity of
this disease, it is important to face its study with an integrated and multilevel approach, from …

This paper presents the needs and requirements that led to the formation of the ACGT
(Advancing Clinico Genomic Trials) integrated project, its vision and methodological …

To support the efficient execution of post-genomic multi-centric clinical trials in breast cancer
we propose a solution that streamlines the assessment of the eligibility of patients for …

The introduction of–omic information within current clinical treatment is one of the main
challenges to transfer the huge amount of genomic-based results. The number of potential …

The challenges regarding seamless integration of distributed, heterogeneous and multilevel
data arising in the context of contemporary, post-genomic clinical trials cannot be effectively …

This paper reports on original results of the Advancing Clinico-Genomic Trials on Cancer
integrated project focusing on the design and development of a European biomedical grid …

The quest for new cancer biomarkers and targets for therapy requires not only the
aggregation and analysis of heterogeneous biomolecular data but also integration of clinical …

In the path towards personalized medicine, the integrative bioinformatics infrastructure is a
critical enabling resource. Until large-scale reference data became available, the attributes …