The Double-Strand Break Landscape of Meiotic Chromosomes Is Shaped by the Paf1 Transcription Elongation Complex in Saccharomyces cerevisiae
SK Gothwal, NJ Patel, MM Colletti, H Sasanuma… - Genetics, 2016 - academic.oup.com
Histone modification is a critical determinant of the frequency and location of meiotic double-
strand breaks (DSBs), and thus recombination. Set1-dependent histone H3K4 methylation …
strand breaks (DSBs), and thus recombination. Set1-dependent histone H3K4 methylation …
Genetic interactions of histone modification machinery Set1 and PAF1C with the recombination complex rec114-mer2-mei4 in the formation of meiotic DNA double …
Y Zhang, T Suzuki, K Li, SK Gothwal… - International Journal of …, 2020 - mdpi.com
Homologous recombination is essential for chromosome segregation during meiosis I.
Meiotic recombination is initiated by the introduction of double-strand breaks (DSBs) at …
Meiotic recombination is initiated by the introduction of double-strand breaks (DSBs) at …
Histone H3 lysine 4 trimethylation marks meiotic recombination initiation sites
The function of histone modifications in initiating and regulating the chromosomal events of
the meiotic prophase remains poorly understood. In Saccharomyces cerevisiae, we …
the meiotic prophase remains poorly understood. In Saccharomyces cerevisiae, we …
Suppression of Meiotic Recombination by CENP-B Homologs in Schizosaccharomyces pombe
P Johansen, HP Cam - Genetics, 2015 - academic.oup.com
Meiotic homologous recombination (HR) is not uniform across eukaryotic genomes, creating
regions of HR hot-and coldspots. Previous study reveals that the Spo11 homolog Rec12 …
regions of HR hot-and coldspots. Previous study reveals that the Spo11 homolog Rec12 …
Dot1-dependent histone H3K79 methylation promotes the formation of meiotic double-strand breaks in the absence of histone H3K4 methylation in budding yeast
Epigenetic marks such as histone modifications play roles in various chromosome dynamics
in mitosis and meiosis. Methylation of histones H3 at positions K4 and K79 is involved in the …
in mitosis and meiosis. Methylation of histones H3 at positions K4 and K79 is involved in the …
Acetylated Histone H3K9 is associated with meiotic recombination hotspots, and plays a role in recombination redundantly with other factors including the H3K4 …
Histone modifications are associated with meiotic recombination hotspots, discrete sites with
augmented recombination frequency. For example, trimethylation of histone H3 lysine4 …
augmented recombination frequency. For example, trimethylation of histone H3 lysine4 …
Histone H3 Lysine 56 Acetylation Is Required for Formation of Normal Levels of Meiotic DNA Breaks in S. cerevisiae
Z Karányi, L Hornyák, L Székvölgyi - Frontiers in cell and …, 2020 - frontiersin.org
Meiotic recombination is initiated by Spo11-catalyzed DNA double-strand breaks (DSBs)
that are promoted by histone modifications and histone modifying enzymes. Herein we …
that are promoted by histone modifications and histone modifying enzymes. Herein we …
The PHD finger protein Spp1 has distinct functions in the Set1 and the meiotic DSB formation complexes
C Adam, R Guérois, A Citarella, L Verardi… - PLoS …, 2018 - journals.plos.org
Histone H3K4 methylation is a feature of meiotic recombination hotspots shared by many
organisms including plants and mammals. Meiotic recombination is initiated by programmed …
organisms including plants and mammals. Meiotic recombination is initiated by programmed …
High-Resolution Global Analysis of the Influences of Bas1 and Ino4 Transcription Factors on Meiotic DNA Break Distributions in Saccharomyces cerevisiae
Meiotic recombination initiates with DNA double-strand breaks (DSBs) made by Spo11. In
Saccharomyces cerevisiae, many DSBs occur in “hotspots” coinciding with nucleosome …
Saccharomyces cerevisiae, many DSBs occur in “hotspots” coinciding with nucleosome …
Scale matters: the spatial correlation of yeast meiotic DNA breaks with histone H3 trimethylation is driven largely by independent colocalization at promoters
SE Tischfield, S Keeney - Cell Cycle, 2012 - Taylor & Francis
During meiosis in many organisms, homologous chromosomes engage in numerous
recombination events initiated by DNA double-strand breaks (DSBs) formed by the Spo11 …
recombination events initiated by DNA double-strand breaks (DSBs) formed by the Spo11 …