YJ Seo, MA Lilliu, G Abu Elghanam… - Journal of tissue …, 2019 - Wiley Online Library
Saliva aids in digestion, lubrication, and protection of the oral cavity against dental caries and oropharyngeal infections. Reduced salivary secretion, below an adequate level to …
M Sakai, T Sakai - Current Protocols, 2022 - Wiley Online Library
The salivary glands produce saliva and are important in maintaining oral health. Saliva keeps the mouth moist, cleanses the oral cavity, aids digestion, and has antibacterial …
A Joraku, CA Sullivan, J Yoo, A Atala - Differentiation, 2007 - Elsevier
This study aimed to achieve functional reconstitution of salivary units from human salivary gland cells in an in vitro three-dimensional culture system. Human salivary cells were …
NJ Leigh, JW Nelson, RE Mellas… - Journal of tissue …, 2017 - Wiley Online Library
Freshly isolated salivary cells can be plated on an extracellular matrix, such as growth factor‐ reduced Matrigel (GFR‐MG), to induce the formation of three‐dimensional (3D) structures …
S Pradhan, C Liu, C Zhang, X Jia… - … —Head and Neck …, 2010 - journals.sagepub.com
Objective: Development of an artificial salivary gland will benefit patients with xerostomia after radiation therapy for upper respiratory cancer. The goal is to devise a three …
MJ Beucler, WE Miller - JoVE (Journal …, 2019 - www-jove-com-443.vpn.cdutcm.edu …
The salivary glands are a site of significant interest for researchers interested in multiple aspects of human disease. One goal of researchers is to restore function of glands damaged …
The use of polarized salivary gland cell monolayers has contributed to our understanding of salivary gland physiology. However, these cell models are not representative of glandular …
Oral mucosa and salivary gland are composed of complex and dynamic networks of extracellular matrix, multiple cell types, vasculature, and various biochemical agents. Two …
Applying tissue engineering principles to design an auto‐secretory device is a potential solution for patients suffering loss of salivary gland function. However, the largest challenge …