Apixaban for the secondary prevention of thrombosis among patients with antiphospholipid syndrome: study rationale and design (ASTRO-APS)

SC Woller, SM Stevens, DA Kaplan… - Clinical and applied …, 2016 - journals.sagepub.com
Background: Antiphospholipid syndrome (APS) is an acquired thrombophilia characterized
by thrombosis, pregnancy morbidity, and the presence of characteristic antibodies. Current …

Protocol modification of apixaban for the secondary prevention of thrombosis among patients with antiphospholipid syndrome study

SC Woller, SM Stevens, DA Kaplan… - Clinical and Applied …, 2018 - journals.sagepub.com
The purpose of this communication is to provide a brief update of our observations to date
that have led to substantive modifications to the study protocol we reported previously in …

Apixaban compared with warfarin to prevent thrombosis in thrombotic antiphospholipid syndrome: a randomized trial

SC Woller, SM Stevens, D Kaplan, TF Wang… - Blood …, 2022 - ashpublications.org
Thrombotic antiphospholipid syndrome (TAPS) is characterized by venous, arterial, or
microvascular thrombosis. Patients with TAPS merit indefinite anticoagulation, and warfarin …

Direct oral anticoagulants use in antiphospholipid syndrome: are these drugs an effective and safe alternative to warfarin? A systematic review of the literature

V Dufrost, J Risse, S Zuily, D Wahl - Current rheumatology reports, 2016 - Springer
Background The cornerstone of thrombotic antiphospholipid syndrome (APS) patients'
management is to prevent recurrent thrombosis by long-term anticoagulation. Purpose of …

Prevention of thrombosis in antiphospholipid syndrome

W Lim - Hematology 2014, the American Society of Hematology …, 2016 - ashpublications.org
Antiphospholipid syndrome (APS) is an acquired autoimmune condition characterized by
thrombotic events, pregnancy morbidity, and laboratory evidence of antiphospholipid …

Factor Xa inhibitors for preventing recurrent thrombosis in patients with antiphospholipid syndrome: a longitudinal cohort study

T Sato, H Nakamura, Y Fujieda, N Ohnishi, N Abe… - Lupus, 2019 - journals.sagepub.com
Objective The objective of this study was to clarify the efficacy and safety of factor Xa
inhibitors for antiphospholipid syndrome patients in real world utilization. Methods This is a …

Direct oral anticoagulants in patients with antiphospholipid syndrome: a cohort study

K Malec, E Broniatowska, A Undas - Lupus, 2020 - journals.sagepub.com
Objectives Despite controversies, direct oral anticoagulants (DOACs) are increasingly used
in antiphospholipid syndrome (APS). We investigated the safety and efficacy of DOACs …

Antithrombotic treatment failures in antiphospholipid syndrome: the new anticoagulants?

H Cohen, SJ Machin - Lupus, 2010 - journals.sagepub.com
Anticoagulation with oral vitamin K antagonists (VKA) is the mainstay of the treatment of
venous and/or arterial thromboembolism in patients with antiphospholipid syndrome (APS) …

Increased risk of thrombosis in antiphospholipid syndrome patients treated with direct oral anticoagulants. Results from an international patient-level data meta …

V Dufrost, J Risse, T Reshetnyak, M Satybaldyeva… - Autoimmunity …, 2018 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are widely used for secondary
prevention of venous thromboembolism (VTE) but their clinical efficacy and safety are not …

[HTML][HTML] Use of direct oral anticoagulants in antiphospholipid syndrome

H Cohen, M Efthymiou, DA Isenberg - Journal of Thrombosis and …, 2018 - Elsevier
The direct oral anticoagulants (DOACs) are therapeutic alternatives to warfarin and other
vitamin K antagonists (VKAs), and constitute the standard of care for many indications. VKAs …