In children, proper growth and development are often regarded as a surrogate marker for
good health. A complex system controls the initiation, rate, and cessation of growth, and thus …

Arabidopsis has 12 histone acetyltransferases grouped in four families: the GNAT/HAG, the
MYST/HAM, the p300/CBP/HAC and the TAFII250/HAF families. We previously showed that …

Lysine acetylation has emerged as a global protein regulation system in all domains of life.
Sirtuins, or Sir2-like enzymes, are a family of histone deacetylases characterized by their …

Nucleosomes impose physical barriers to DNA-templated processes, playing important roles
in eukaryotic gene regulation. DNA is packaged into nucleosomes by histone proteins …

Human epidemiological studies worldwide have provided convincing support for the
concept of developmental programming. The concept of developmental programming was …

Till recently, knowledge about epigenetic regulation in bacterial world confined largely to
DNA methylation. Lysine acetylation/deacetylation of histones is a major contributor for …

Histone modifiers regulate proper cellular activities in response to various environmental
stress by modulating gene expression. In budding yeast, Rph1 transcriptionally represses …

Lysine acetylation is a reversible and highly regulated post-translational modification that
plays a critical role in regulating many aspects of cellular processes, both in bacteria and in …

Endocrine disrupting chemicals (EDCs) are classes of environmental contaminants whose
exposure even at very low concentrations interfere with normal endocrine signaling and …

Aminoacyl‐tRNA synthetases (aaRSs) play essential roles in protein synthesis. As a
member of the aaRS family, the tyrosyl‐tRNA synthetase (TyrRS) in Escherichia coli has …