Introduction Genetic constitution and inflammation both contribute to development of
coronary artery disease (CAD). Several CAD-associated single-nucleotide polymorphisms …

Calcification of vessels is strongly associated with atherosclerosis and leads to coronary
artery disease (CAD) and myocardial infarction (MI). Genome-wide association studies …

Background and aims Conventional coronary artery disease (CAD) risk factors like age,
gender, blood lipids, hypertension and smoking have been the basis of CAD risk prediction …

The interleukin 1 family plays an important role in the immune and inflammatory responses.
Coronary artery disease (CAD) is a chronic inflammatory disease. However, the genetic …

GWAS have identified hundreds of height-associated loci. However, determining causal
mechanisms is challenging, especially since height-relevant tissues (eg growth plates) are …

Genome-wide association studies (GWAS) have been successfully applied in identifying
single nucleotide polymorphisms (SNPs) associated with body mass index (BMI) and …

To clarify the role of thyroid function in ischemic heart disease (IHD) we assessed IHD risk
and risk factors according to genetically predicted thyroid stimulating hormone (TSH), free …

Coronary artery disease (CAD) is a leading cause of mortality globally. However, the
etiology and pathogenesis of CAD are not fully understood. The aim of the present meta …

Atherosclerotic cardiovascular disease (CVD) is a leading cause of mortality and morbidity
worldwide, with coronary artery disease (CAD) being the single leading cause of death …

During the last decade, genome-wide association studies (GWAS) have represented a
major approach to dissect complex human genetic diseases. Due in part to limited statistical …