Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain

CM Schumann, FR Sharp, BP Ander, B Stamova - Molecular autism, 2017 - Springer
Background Autism spectrum disorder (ASD) is sexually dimorphic in brain structure,
genetics, and behaviors. In studies of brain tissue, the age of the population is clearly a …

Bio-collections in autism research

J Reilly, L Gallagher, JL Chen, G Leader, S Shen - Molecular Autism, 2017 - Springer
Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders with
diverse clinical manifestations and symptoms. In the last 10 years, there have been …

Skin transcriptome reveals the intrinsic molecular mechanisms underlying hair follicle cycling in Cashmere goats under natural and shortened photoperiod conditions

M Yang, S Song, K Dong, XF Chen, X Liu, M Rouzi… - Scientific reports, 2017 - nature.com
The growth of cashmere exhibits a seasonal pattern arising from photoperiod change.
However, the underlying molecular mechanism remains unclear. We profiled the skin …

Integrative genomic analyses for identification and prioritization of long non-coding RNAs associated with autism

BL Gudenas, AK Srivastava, L Wang - PLoS One, 2017 - journals.plos.org
Genetic studies have identified many risk loci for autism spectrum disorder (ASD) although
causal factors in the majority of cases are still unknown. Currently, known ASD risk genes …

Hierarchical cortical transcriptome disorganization in autism

MV Lombardo, E Courchesne, NE Lewis, T Pramparo - Molecular Autism, 2017 - Springer
Background Autism spectrum disorders (ASD) are etiologically heterogeneous and complex.
Functional genomics work has begun to identify a diverse array of dysregulated …

A cell type‐specific expression signature predicts haploinsufficient autism‐susceptibility genes

C Zhang, Y Shen - Human mutation, 2017 - Wiley Online Library
Recent studies have identified many genes with rare de novo mutations in autism, but a
limited number of these have been conclusively established as disease‐susceptibility genes …

Social isolation alters social and mating behavior in the R451C neuroligin mouse model of autism

EL Burrows, AF Eastwood, C May, SC Kolbe… - Neural …, 2017 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental disorder typified by impaired
social communication and restrictive and repetitive behaviors. Mice serve as an ideal …

The co‐occurrence of Down syndrome and autism spectrum disorder: is it because of additional genetic variations?

AL Rachubinski, S Hepburn, ER Elias… - Prenatal …, 2017 - Wiley Online Library
Individuals with Down syndrome (DS) are diagnosed with autism spectrum disorder (ASD) at
a significantly higher frequency than the typical population. The differentiation of ASD …

RNA sequencing of transformed lymphoblastoid cells from siblings discordant for autism spectrum disorders reveals transcriptomic and functional alterations …

DS Tylee, AJ Espinoza, JL Hess, MA Tahir… - Autism …, 2017 - Wiley Online Library
Genome‐wide expression studies of samples derived from individuals with autism spectrum
disorder (ASD) and their unaffected siblings have been widely used to shed light on …

[HTML][HTML] Immune contributions to cause and effect in autism spectrum disorder

AK McAllister - Biological psychiatry, 2017 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that appears during the
first 3 years of life and presents with a variable set of symptoms that include impairments in …