Objectives: Lithium remains the oldest and most effective treatment for mood stabilisation in
bipolar disorder (BD), even though at least half of patients are only partially responsive or do …

We present here the hypothesis that alternative poly-adenylation (APA) is dysregulated in
the brains of individuals affected by Autism Spectrum Disorder (ASD), due to disruptions in …

Alternative splicing is a powerful mechanism that largely expands the coding potential of
eukaryotic genomes. Indeed, its complex and flexible regulation is exploited by cells to …

Detailed anatomical tracing and mapping of the viscerotopic organization of the vagal motor
nuclei has provided insight into autonomic function in health and disease. To further define …

Bladder cancer (BC) is a common urinary system tumor with high aggressiveness, and it
results in relatively high mortality due to a lack of precise and suitable biomarkers. In this …

Background Autism spectrum disorders (ASD) are hereditary, heterogeneous and
biologically complex neurodevelopmental disorders. Individual studies on gene expression …

It is often assumed, but not established, that the major neurodegenerative diseases, such as
Parkinson's disease, are not just age-dependent (their incidence changes with time) but …

Until recently autism spectrum disorder (ASD) was regarded as a neurodevelopmental
condition with unknown causes and pathogenesis. In the footsteps of the revolution of …

Abstract Post-Traumatic Stress Disorder (PTSD) is a psychiatric disorder that develops in
individuals experiencing a shocking incident, but the underlying disease susceptibility gene …

Abstract Autism Spectrum Disorder (ASD) and Tourette syndrome (TS) are poorly
understood neurodevelopment disorders with strong male bias, high heritability and …