Background Multidrug-resistant tuberculosis poses a major threat to the success of
tuberculosis control programs worldwide. Understanding how drug-resistant tuberculosis …

Background Tuberculosis is a serious infectious disease affecting millions of people. In spite
of efforts to reduce the disease, increasing antibiotic resistance has contributed to persist in …

Genomics has significantly revolutionized pathogen surveillance, particularly in
epidemiological studies, the detection of drug-resistant strains, and disease control. Despite …

Peru has the highest burden of multidrug-resistant tuberculosis in the Americas region.
Since 1999, the annual number of extensively drug-resistant tuberculosis (XDR-TB) …

Objectives Thousands of cases of multidrug-resistant tuberculosis (TB) have been observed
in the Philippines, but studies on the Mycobacterium tuberculosis (MTB) genotypes that …

Background Whole genome sequencing (WGS) has been proposed as a tool for diagnosing
drug resistance in tuberculosis. However, reports of its effectiveness in endemic countries …

Background Mexico is one of the most important contributors of drug and multidrug-resistant
tuberculosis in Latin America; however, knowledge of the genetic diversity of drug-resistant …

Mycobacterium tuberculosis (M. tuberculosis) was the pathogen responsible for the highest
number of deaths from infectious diseases in the world, before the arrival of the COVID-19 …

Tuberculosis (TB) is one of the leading causes of death due to an infectious disease in the
world. Understanding the mechanisms of drug resistance has become pivotal in the …

Drug resistance (DR) remains a global challenge in tuberculosis (TB) control. In order to
develop molecular-based diagnostic methods to replace the traditional culture-based …